CRISPR-Cas9 is an RNA-mediated adaptive immune system that protects bacteria and
archaea from viruses or plasmids. Herein we discuss the recent development of CRISPR …

Numerous photoreceptors and genetic circuits emerged over the past two decades and now
enable the light-dependent ie, optogenetic, regulation of gene expression in bacteria …

Bacteria of the order Actinomycetales are one of the most important sources of
pharmacologically active and industrially relevant secondary metabolites. Unfortunately …

CRISPRi is a powerful technique to repress gene expression in a targeted and highly
efficient manner. However, this potency is a double-edged sword in inducible systems, as …

Synthetic biology has developed rapidly in the 21st century. It covers a range of scientific
disciplines that incorporate principles from engineering to take advantage of and improve …

The ability to modulate gene expression is crucial for studying gene function and
programming cell behaviors. Combining the reliability of CRISPRi and the precision of …

Pinosylvin as a bioactive stilbene is of great interest for food supplements and
pharmaceuticals development. In comparison to conventional extraction of pinosylvin from …

Abstract Intracellular products (eg, insulin), which are obtained through cell lysis, take up a
big share of the biotech industry. It is often time-consuming, laborious, and environment …

The ability to modulate gene expression is crucial for studying gene function and
programming cell behaviors. Combining the reliability of CRISPRi and the precision of …

Although bio-based fuels and chemicals offer an appealing and more sustainable
alternative to traditional petroleum-based fuels and chemicals, their widespread acceptance …