Current and emerging therapies for corneal neovascularization

D Roshandel, M Eslani, A Baradaran-Rafii… - The ocular …, 2018 - Elsevier
The cornea is unique because of its complete avascularity. Corneal neovascularization
(CNV) can result from a variety of etiologies including contact lens wear; corneal infections; …

[HTML][HTML] Up-to-date molecular medicine strategies for management of ocular surface neovascularization

Y Yang, J Zhong, D Cui, LD Jensen - Advanced Drug Delivery Reviews, 2023 - Elsevier
Ocular surface neovascularization and its resulting pathological changes significantly alter
corneal refraction and obstruct light path to the retina, and hence is a major cause of vision …

Therapeutic strategies for restoring perturbed corneal epithelial homeostasis in limbal stem cell deficiency: current trends and future directions

F Masood, JH Chang, A Akbar, A Song, WY Hu… - Cells, 2022 - mdpi.com
Limbal stem cells constitute an important cell population required for regeneration of the
corneal epithelium. If insults to limbal stem cells or their niche are sufficiently severe, a …

A systematic review of cellular therapies for the treatment of limbal stem cell deficiency affecting one or both eyes

FC Figueiredo, JM Glanville, M Arber, E Carr… - The Ocular Surface, 2021 - Elsevier
Purpose This systematic review (SR) assessed the efficacy, safety and cost-effectiveness of
cell-based therapy to manage limbal stem cell deficiency (LSCD), a sight-threatening …

Comparison of optical coherence tomography angiography to indocyanine green angiography and slit lamp photography for corneal vascularization in an animal …

TP Stanzel, K Devarajan, NC Lwin, GH Yam… - Scientific reports, 2018 - nature.com
Corneal neovascularization (CoNV) could be treated by novel anti-angiogenic therapies,
though reliable and objective imaging tools to evaluate corneal vasculature and treatment …

Concise review: altered versus unaltered amniotic membrane as a substrate for limbal epithelial cells

TP Utheim, Ø Aass Utheim, P Salvanos… - Stem Cells …, 2018 - academic.oup.com
Limbal stem cell deficiency (LSCD) can result from a variety of corneal disorders, including
chemical and thermal burns, infections, and autoimmune diseases. The symptoms of LSCD …

Oral mucosal stem cells, human immature dental pulp stem cells and hair follicle bulge stem cells as adult stem cells able to correct limbal stem cell deficiency

NT Hassan, NA AbdelAziz - Current Stem Cell Research & …, 2018 - ingentaconnect.com
Background: Adult stem cells are somatic stem cells distributed all over the body. They
represent a promising future for regenerative medicine because of their multiple advantages …

Orphan drug approvals of 2014: Europe and the United States

P Norman - Expert Opinion on Orphan Drugs, 2015 - Taylor & Francis
Introduction: The development of orphan drugs for the treatment of rare diseases has
attracted increasing interest from the pharmaceutical industry. The year 2014 saw an …

[PDF][PDF] TISSUEENGINEERING ANDREGENERATIVEMEDICINE

TORP UTHEIM, ØA UTHEIM, P SALVANOS… - academia.edu
Limbal stem cell deficiency (LSCD) can result from a variety of corneal disorders, including
chemical and thermal burns, infections, and autoimmune diseases. The symptoms of LSCD …

Orphan drug approvals of 2015: Europe and the United States

P Norman - Expert Opinion on Orphan Drugs, 2016 - Taylor & Francis
Introduction: The development of orphan drugs for the treatment of rare diseases has
attracted increasing interest from the pharmaceutical industry. The level of European …