Epigenetic regulation of gene expression has been ultimately linked to cancer development,
with posttranslational histone modifications representing attractive targets for disease …

Advances achieved with molecular biology and genomics technologies have permitted
investigators to discover epigenetic mechanisms, such as DNA methylation and histone …

Alcohol use disorder (AUD) is a complex brain disorder with an array of persistent
behavioral and neurochemical manifestations. Both genetic and environmental factors are …

The SET Domain Bifurcated Histone Lysine Methyltransferase 1 (SETDB1) is a prominent
member of the Suppressor of Variegation 3–9 (SUV39)-related protein lysine …

This review covers molecular mechanisms involving oxidative stress and DNA damage that
may contribute to morphological and functional developmental disorders in animal models …

Epigenetic regulation is a process that takes place through adaptive cellular pathways
influenced by environmental factors and metabolic changes to modulate gene activity with …

Parkinson's disease (PD) is a common neurodegenerative disorder caused by genetic,
epigenetic, and environmental factors. Recent advance in genomics and epigenetics have …

Accumulating evidence indicates that the fetal environment plays an important role in brain
development and sets the brain on a trajectory across the life span. An abnormal fetal …

The preconception environment is a significant modifier of dysgenesis and the development
of environmentally-induced disease. To date, fetal alcohol spectrum disorders (FASDs) have …

The actions of cannabis are mediated by G protein-coupled receptors that are part of an
endogenous cannabinoid system (ECS). ECS consists of the naturally occurring ligands N …