RNA Degradation in Saccharomyces cerevisae
R Parker - Genetics, 2012 - academic.oup.com
All RNA species in yeast cells are subject to turnover. Work over the past 20 years has
defined degradation mechanisms for messenger RNAs, transfer RNAs, ribosomal RNAs …
defined degradation mechanisms for messenger RNAs, transfer RNAs, ribosomal RNAs …
Multisubunit RNA polymerases IV and V: purveyors of non-coding RNA for plant gene silencing
JR Haag, CS Pikaard - Nature reviews Molecular cell biology, 2011 - nature.com
In all eukaryotes, nuclear DNA-dependent RNA polymerases I, II and III synthesize the
myriad RNAs that are essential for life. Remarkably, plants have evolved two additional …
myriad RNAs that are essential for life. Remarkably, plants have evolved two additional …
A dual program for translation regulation in cellular proliferation and differentiation
A dichotomous choice for metazoan cells is between proliferation and differentiation.
Measuring tRNA pools in various cell types, we found two distinct subsets, one that is …
Measuring tRNA pools in various cell types, we found two distinct subsets, one that is …
[HTML][HTML] Gene expression is circular: factors for mRNA degradation also foster mRNA synthesis
Maintaining proper mRNA levels is a key aspect in the regulation of gene expression. The
balance between mRNA synthesis and decay determines these levels. We demonstrate that …
balance between mRNA synthesis and decay determines these levels. We demonstrate that …
Comparative dynamic transcriptome analysis (cDTA) reveals mutual feedback between mRNA synthesis and degradation
To monitor eukaryotic mRNA metabolism, we developed comparative dynamic
transcriptome analysis (cDTA). cDTA provides absolute rates of mRNA synthesis and decay …
transcriptome analysis (cDTA). cDTA provides absolute rates of mRNA synthesis and decay …
A quantitative inventory of yeast P body proteins reveals principles of composition and specificity
P bodies are archetypal biomolecular condensates that concentrate proteins and RNA
without a surrounding membrane. While dozens of P body proteins are known, the …
without a surrounding membrane. While dozens of P body proteins are known, the …
Defining the RNA interactome by total RNA‐associated protein purification
V Shchepachev, S Bresson, C Spanos… - Molecular systems …, 2019 - embopress.org
The RNA binding proteome (RBP ome) was previously investigated using UV crosslinking
and purification of poly (A)‐associated proteins. However, most cellular transcripts are not …
and purification of poly (A)‐associated proteins. However, most cellular transcripts are not …
The intimate relationships of mRNA decay and translation
B Roy, A Jacobson - Trends in Genetics, 2013 - cell.com
The decay rate of an mRNA and the efficiency with which it is translated are key
determinants of eukaryotic gene expression. Although it was once thought that mRNA …
determinants of eukaryotic gene expression. Although it was once thought that mRNA …
Eukaryotic mRNA decay: methodologies, pathways, and links to other stages of gene expression
Abstract mRNA concentration depends on the balance between transcription and
degradation rates. On both sides of the equilibrium, synthesis and degradation show …
degradation rates. On both sides of the equilibrium, synthesis and degradation show …
[HTML][HTML] Promoter elements regulate cytoplasmic mRNA decay
A Bregman, M Avraham-Kelbert, O Barkai, L Duek… - Cell, 2011 - cell.com
Promoters are DNA elements that enable transcription and its regulation by trans-acting
factors. Here, we demonstrate that yeast promoters can also regulate mRNA decay after the …
factors. Here, we demonstrate that yeast promoters can also regulate mRNA decay after the …