[HTML][HTML] EMT mechanism in breast cancer metastasis and drug resistance: Revisiting molecular interactions and biological functions

M Hashemi, HZ Arani, S Orouei, S Fallah… - Biomedicine & …, 2022 - Elsevier
One of the malignant tumors in women that has involved both developed and developing
countries is breast cancer. Similar to other types of tumors, breast cancer cells demonstrate …

Parthenolide induces ROS-mediated apoptosis in lymphoid malignancies

J Jorge, J Neves, R Alves, C Geraldes… - International Journal of …, 2023 - mdpi.com
Lymphoid malignancies are a group of highly heterogeneous diseases frequently
associated with constitutive activation of the nuclear factor kappa B (NF-κB) signaling …

[HTML][HTML] Exploring the Phytochemistry, Signaling Pathways, and Mechanisms of Action of Tanacetum parthenium (L.) Sch.Bip.: A Comprehensive Literature Review

A Kashkooe, A Jalali, MM Zarshenas, A Hamedi - Biomedicines, 2024 - mdpi.com
The traditional use of Tanacetum parthenium (L.) Sch. Bip., commonly known as feverfew,
extends across various medical conditions, notably those associated with pain and …

eIF4A/PDCD4 pathway, a factor for doxorubicin chemoresistance in a triple-negative breast cancer cell model

A González-Ortiz, A Pulido-Capiz… - Cells, 2022 - mdpi.com
Cells employ several adaptive mechanisms under conditions of accelerated cell division,
such as the unfolded protein response (UPR). The UPR is composed of a tripartite signaling …

Parthenolide inhibits the proliferation and migration of cervical cancer cells via FAK/GSK3β pathway

L Huang, F Liu, X Liu, L Niu, L Sun, F Fang… - Cancer Chemotherapy …, 2024 - Springer
Purpose Cervical cancer (CC) ranks as the fourth most prevalent malignancy among women
worldwide, necessitating effective therapeutic interventions to mitigate its detrimental impact …

[HTML][HTML] Downregulation of the enhancer of zeste homolog 1 transcriptional factor predicts poor prognosis of triple-negative breast cancer patients

W Peng, W Tang, JD Li, RQ He, JY Luo, ZX Chen… - PeerJ, 2022 - peerj.com
Background Triple-negative breast cancer (TNBC) is the most malignant subtype of breast
cancer and lacks effective biomarkers. This study seeks to unravel the expression status and …

Parthenolide induces ROS-dependent cell death in human gastric cancer cell.

D Han, W Zhu, Y Chen, H Wang - Advances in Clinical & …, 2024 - search.ebscohost.com
Abstract Background: Parthenolide (PN), a key active ingredient of feverfew, has been used
to treat gastrointestinal disorders. However, the mechanism of the cytotoxic effect exerted by …