Tooth number is abnormal in about 20% of the human population. The most common defect
is agenesis of the third molars, followed by loss of the lateral incisors and loss of the second …

Pregnancy and parturition are intricately regulated to ensure successful reproductive
outcomes. However, the factors that control gestational length in humans and other …

The X-linked DEAD-box RNA helicase DDX3 (DDX3X) is a multifunctional protein that has
been implicated in gene regulation, cell cycle control, apoptosis, and tumorigenesis …

In eutherian mammals, embryonic growth and survival is dependent on the formation of the
placenta, an organ that facilitates the efficient exchange of oxygen, nutrients, and metabolic …

Fetal growth restriction (FGR) is an adverse pregnancy outcome associated with significant
perinatal and paediatric morbidity and mortality, and an increased risk of chronic disease …

Resistance gene–mediated immunity confers protection against pathogen infection in a
wide range of plants. A genetic screen for Arabidopsis thaliana mutants compromised for …

Despite participation in overlapping metabolic pathways, the relationship between choline
and vitamin B-12 has not been well characterized especially during pregnancy. We sought …

A 4 base-pair deletion mutation in the Distal-less 3 (DLX3) gene is etiologic for Tricho–
Dento–Osseous syndrome (TDO). A cardinal feature of TDO is an increased thickness and …

Placental growth factor (PGF) is abundantly expressed by trophoblast cells within human
placentae and is important for trophoblast development and placental vascularization …

The placental transcription factors Distal-less 3 (DLX3) and Glial cell missing-1 (GCM1)
have been shown to coordinate the specific regulation of PGF in human trophoblast cell …