Recent progress on gene-deleted live-attenuated African swine fever virus vaccines

HLX Vu, DS McVey - npj Vaccines, 2024 - nature.com
Abstract African Swine Fever (ASF) is a highly lethal viral disease in swine, with mortality
rates approaching 100%. The disease has spread to many swine-producing countries …

African swine fever modified live vaccine candidates: Transitioning from discovery to product development through harmonized standards and guidelines

DA Brake - Viruses, 2022 - mdpi.com
The recent centennial anniversary of RE Montgomery's seminal published description of “a
form of swine fever” disease transmitted from wild African pigs to European domestic pigs is …

Stability of African swine fever virus in carcasses of domestic pigs and wild boar experimentally infected with the ASFV “Estonia 2014” isolate

M Fischer, J Hühr, S Blome, FJ Conraths, C Probst - Viruses, 2020 - mdpi.com
Europe is currently experiencing a long-lasting African swine fever (ASF) epidemic, both in
domestic pigs and wild boar. There is great concern that carcasses of infected wild boar may …

African swine fever virus cysteine protease pS273R inhibits pyroptosis by noncanonically cleaving gasdermin D

G Zhao, T Li, X Liu, T Zhang, Z Zhang, L Kang… - Journal of Biological …, 2022 - ASBMB
African swine fever (ASF) is a viral hemorrhagic disease that affects domestic pigs and wild
boar and is caused by the African swine fever virus (ASFV). The ASFV virion contains a long …

Adaptation of African swine fever virus to HEK293T cells

T Wang, L Wang, Y Han, L Pan, J Yang… - Transboundary and …, 2021 - Wiley Online Library
African swine fever (ASF), caused by African swine fever virus (ASFV), is a highly contagious
disease with high morbidity and mortality in domestic pigs. Although adaptation of ASFV to …

[HTML][HTML] A simple nanobody-based competitive ELISA to detect antibodies against African swine fever virus

J Zhao, J Zhu, Y Wang, M Yang, Q Zhang, C Zhang… - Virologica Sinica, 2022 - Elsevier
African swine fever virus (ASFV) infection is a big threat to the global pig industry. Because
there is no effective vaccine, rapid, low-cost, and simple diagnosis methods are necessary to …

African swine fever virus structural protein p17 inhibits cell proliferation through ER stress—ROS mediated cell cycle arrest

N Xia, H Wang, X Liu, Q Shao, D Ao, Y Xu, S Jiang… - Viruses, 2020 - mdpi.com
African swine fever virus (ASFV) is a highly pathogenic large DNA virus that causes African
swine fever (ASF) in domestic pigs and wild boars. The p17 protein, encoded by the D117L …

Six adenoviral vectored African swine fever virus genes protect against fatal disease caused by genotype I challenge

R Portugal, H Goldswain, R Moore, M Tully… - Journal of …, 2024 - journals.asm.org
African swine fever virus causes a lethal hemorrhagic disease in domestic swine and wild
boar for which currently licensed commercial vaccines are only available in Vietnam …

CD1d facilitates African swine fever virus entry into the host cells via clathrin-mediated endocytosis

X Chen, J Zheng, C Liu, T Li, X Wang, X Li… - Emerging Microbes & …, 2023 - Taylor & Francis
African swine fever (ASF) is a highly contagious and acute hemorrhagic viral disease with
high morbidity and mortality in domestic pigs and wild boars. The disease has become a …

Development real-time PCR assays to genetically differentiate vaccinated pigs from infected pigs with the Eurasian strain of African swine fever virus

L Velazquez-Salinas, E Ramirez-Medina… - Frontiers in Veterinary …, 2021 - frontiersin.org
Currently, African swine fever virus (ASFV) represents one of the most important economic
threats for the global pork industry. Recently, significant advances have been made in the …