Polyethylene glycol: A promising approach for sustainable organic synthesis

J Soni, N Sahiba, A Sethiya, S Agarwal - Journal of Molecular Liquids, 2020 - Elsevier
Over the last decade, polyethylene glycol (PEG) has emerged as a green and inexpensive
catalyst as well as a solvent in a number of chemical transformations. It serves as a stable …

Brønsted acid-promoted synthesis of common heterocycles and related bio-active and functional molecules

S Ponra, KC Majumdar - RSC advances, 2016 - pubs.rsc.org
Various heterocyclic systems based on natural and unnatural biologically active products
were synthesized by Brønsted acid-promoted cyclization. We have made an attempt to …

[HTML][HTML] A review of synthetic methods of 1, 2, 4-triazolopyridines and their therapeutic properties

SP Melal, NO Mahmoodi - Results in Chemistry, 2023 - Elsevier
This review summarizes data on the synthesis of important aromatic core [1, 2, 4]
triazolopyridines. The presented methods are classified according to the types of reagents …

PTSA-catalyzed selective synthesis and antibacterial evaluation of 1, 2-disubstituted benzimidazoles

J Fu, Y Yue, K Liu, S Wang, Y Zhang, Q Su, Q Gu… - Molecular Diversity, 2023 - Springer
Herein, we developed a convenient and efficient method via protonation of p-toluenesulfonic
acid promoted cyclocondensation of o-phenylenediamine and aldehydes for selectively …

p-Toluenesulfonic acid-promoted organic transformations for the generation of molecular complexity

S Pal, D Das, S Bhunia - Organic & Biomolecular Chemistry, 2024 - pubs.rsc.org
Since the beginning of this century, p-toluenesulfonic acid (p-TSA) catalyzed organic
transformations have been an active area of research in pursuit of developing efficient …

Iodine-catalyzed formation of substituted 2-aminobenzothiazole derivatives in PEG 400

G Dumonteil, MA Hiebel, MC Scherrmann… - RSC …, 2016 - pubs.rsc.org
An iodine-catalyzed formation of substituted 2-aminobenzothiazole derivatives is herein
described using hydrogen peroxide as an oxidant in PEG400. The method enabled an …

Hit-to-lead optimization of novel benzimidazole phenylacetamides as broad spectrum trypanosomacides

N McNamara, R Rahmani, ML Sykes… - RSC Medicinal …, 2020 - pubs.rsc.org
Trypanosoma cruzi and Trypanosoma brucei are the parasitic causative agents of Chagas
disease and human African trypanosomiasis (HAT), respectively. The drugs currently used …

Green solvents for eco-friendly synthesis of bioactive heterocycles

AV Dolzhenko - Green Synthetic Approaches for Biologically Relevant …, 2021 - Elsevier
Use of safer solvents satisfies green chemistry practices. From the green chemistry
perspective the best solvent for reactions is no solvent. However, this ideal situation is not …

PTSA.H2O‐Catalyzed Reaction of 3‐Aminocoumarins and Phenylacetaldehydes: A Route to Access Various Pyrido(2,3‐c)coumarin Derivatives

M Belal, AT Khan - ChemistrySelect, 2017 - Wiley Online Library
Abstract A number of pyrido (2, 3‐c) coumarin derivatives were accomplished from various 3‐
aminocoumarins and phenylacetaldehydes in acetonitrile using 10 mol% p‐toluenesulfonic …

Methods to access 2-aminobenzimidazoles of medicinal importance

A Cruz, IIP Martínez… - Current Organic …, 2019 - benthamdirect.com
Benzimidazole (BI) and derivatives are interesting because several of these compounds
have been found to have a diversity of biological activities with clinical applications. In view …