The proteins extracellular signal-regulated kinase 1 (ERK1) and ERK2 are the downstream
components of a phosphorelay pathway that conveys growth and mitogenic signals largely …

Simple Summary In this review, we describe arginine's role as a signaling metabolite,
epigenetic regulator and mitochondrial modulator in cancer cells, and summarize recent …

We present a proteogenomic study of 108 human papilloma virus (HPV)-negative head and
neck squamous cell carcinomas (HNSCCs). Proteomic analysis systematically catalogs …

The causative agent of the coronavirus disease 2019 (COVID-19) pandemic, severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has infected millions and killed …

Mammalian target of rapamycin (mTOR) is a highly conserved Serine/Threonine (Ser/Thr)
protein kinase, which belongs to phosphatidylinositol-3-kinase-related kinase (PIKK) protein …

mTOR [mechanistic target of rapamycin] is a serine/threonine protein kinase that, as part of
mTORC1 (mTOR complex 1), acts as an important molecular connection between nutrient …

The mechanistic/mammalian target of rapamycin (mTOR) plays a master role in cell
proliferation and growth in response to insulin, amino acids, energy levels, and oxygen …

The stage at which ribosomes are recruited to messenger RNAs (mRNAs) is an elaborate
and highly regulated phase of protein synthesis. Upon completion of this step, a ribosome is …

Although covalent inhibitors have been used as therapeutics for more than a century, there
has been general resistance in the pharmaceutical industry against their further …

Characterizing the interactions that SARS-CoV-2 viral RNAs make with host cell proteins
during infection can improve our understanding of viral RNA functions and the host innate …