Molecular mechanisms in autoimmune thyroid disease
H Vargas-Uricoechea - Cells, 2023 - mdpi.com
The most common cause of acquired thyroid dysfunction is autoimmune thyroid disease,
which is an organ-specific autoimmune disease with two presentation phenotypes …
which is an organ-specific autoimmune disease with two presentation phenotypes …
Iodide handling disorders (nis, tpo, tg, iyd)
HM Targovnik, CE Citterio, CM Rivolta - Best Practice & Research Clinical …, 2017 - Elsevier
Iodide Handling Disorders lead to defects of the biosynthesis of thyroid hormones (thyroid
dyshormonogenesis, TD) and thereafter congenital hypothyroidism (CH), the most common …
dyshormonogenesis, TD) and thereafter congenital hypothyroidism (CH), the most common …
Mutation spectrum in TPO gene of Bangladeshi patients with thyroid dyshormonogenesis and analysis of the effects of different mutations on the structural features …
Although thyroid dyshormonogenesis (TDH) accounts for 10‐20% of congenital
hypothyroidism (CH), the molecular etiology of TDH is unknown in Bangladesh. Thyroid …
hypothyroidism (CH), the molecular etiology of TDH is unknown in Bangladesh. Thyroid …
Newborn screening and single nucleotide variation profiling of TSHR, TPO, TG and DUOX2 candidate genes for congenital hypothyroidism
Y Kollati, RRD Akella, SM Naushad, D Borkar… - Molecular Biology …, 2020 - Springer
High prevalence of congenital hypothyroidism (CH) among Indian newborns prompted us to
establish population-specific reference ranges of TSH and to explore the contribution of the …
establish population-specific reference ranges of TSH and to explore the contribution of the …
High-resolution melt curve analysis: An approach for variant detection in the TPO gene of congenital hypothyroid patients in Bangladesh
TPO (Thyroid Peroxidase) is known to be one of the major genes involved in congenital
hypothyroid patients with thyroid dyshormonogenesis. The present study aims to validate …
hypothyroid patients with thyroid dyshormonogenesis. The present study aims to validate …
Curating the gnomAD database: report of novel variants in the thyroid peroxidase gene using in silico bioinformatics algorithms and a literature review
MF Molina, MG Pio, KG Scheps, E Adrover… - Molecular and Cellular …, 2022 - Elsevier
Thyroid peroxidase (TPO) is a membrane-bound glycoprotein located at the apical side of
the thyroid follicular cells that catalyzes both iodination and coupling of iodotyrosine …
the thyroid follicular cells that catalyzes both iodination and coupling of iodotyrosine …
The epigenetic mechanisms of adaption to the hot and humid climate in Hu sheep (Ovis aries)
H Ren, J Jiang, J Li, X Sun, C Chen, L Liu… - Physiological …, 2024 - Wiley Online Library
Hu sheep is characterized by its excellent fecundity and high adaptability to various
ecological environments. To reveal the molecular basis involved in Hu sheep, we first …
ecological environments. To reveal the molecular basis involved in Hu sheep, we first …
Association between TPO Asn698Thr and Thr725Pro gene polymorphisms and serum anti-TPO levels in Iranian patients with subclinical hypothyroidism
A Khoshi, A Sirghani, M Ghazisaeedi… - Hormones, 2017 - Springer
OBJECTIVE Subclinical hypothyroidism (SCH) is defined as high levels of TSH in the
presence of normal levels of serum FT4. Since thyroid peroxidase (TPO) plays a key role in …
presence of normal levels of serum FT4. Since thyroid peroxidase (TPO) plays a key role in …
Association of thyroid peroxidase gene polymorphisms and serum anti-TPO levels in Egyptian patients with autoimmune hypothyroidism
HS Ahmed, AAM Nsrallah… - … Metabolic & Immune …, 2021 - ingentaconnect.com
Background: Thyroid peroxidase (TPO) gene mutation leads to a change in enzyme built
structure resulting in the anti-TPO autoantibodies production that may cause thyroid …
structure resulting in the anti-TPO autoantibodies production that may cause thyroid …
[HTML][HTML] Unexpected high frequency of anti-thyroid peroxidase (anti-TPO) antibodies in Golestan province, Iran
H Heidarpour, F Hooshmand, FI Amlashi… - Caspian Journal of …, 2023 - ncbi.nlm.nih.gov
Background: Anti-TPO antibodies are one of the characteristic factors in autoimmune
thyroiditis (AIT). Previous studies reported a high prevalence of anti-TPO antibodies (Abs) in …
thyroiditis (AIT). Previous studies reported a high prevalence of anti-TPO antibodies (Abs) in …