The history of brain drug delivery is reviewed beginning with the first demonstration, in 1914,
that a drug for syphilis, salvarsan, did not enter the brain, due to the presence of a blood …

New Developments in Liposomal Drug Delivery | Chemical Reviews ACS ACS Publications
C&EN CAS Find my institution Log In Chemical Reviews ACS Publications. Most Trusted. Most …

Targeted drug and gene delivery is the key for precision therapy. Lipid nanoparticles as non-
viral vectors have attracted extensive attentions in treating a variety of diseases, such as …

The filamentous bacteriophage fd bind a cell target with exquisite specificity through its few
copies of display peptides, whereas nanoparticles functionalized with hundreds to …

Central nervous system (CNS) diseases are among the most difficult to treat, mainly
because the vast majority of the drugs fail to cross the blood-brain barrier (BBB) or to reach …

The complement system, professional phagocytes and other cells such as Natural killer cells
and mast cells are among the important components of the innate arm of the immune …

Phage therapy has re-emerged as a promising solution for combating antimicrobial-resistant
bacterial infections. Increasingly, studies have revealed that phages possess therapeutic …

Peptides are small biological molecules that are attractive in drug delivery and materials
engineering for applications including therapeutics, molecular building blocks and cell …

The blood-brain barrier (BBB), the unusual microvascular endothelial interface between the
central nervous system (CNS) and the circulatory system, is a major hindrance to drug …

Abstract Treatment of medulloblastoma (MB) is challenging due to diverse genetic make-up,
chemoresistance and inefficient drug transport across the blood brain barrier (BBB). Since …