Disialoganglioside GD2 expression in solid tumors and role as a target for cancer therapy

B Nazha, C Inal, TK Owonikoko - Frontiers in Oncology, 2020 - frontiersin.org
Gangliosides are carbohydrate-containing sphingolipids that are widely expressed in
normal tissues, making most subtypes unsuitable as targets for cancer therapy. However …

Targeting tumor glycans for cancer therapy: successes, limitations, and perspectives

N Berois, A Pittini, E Osinaga - Cancers, 2022 - mdpi.com
Simple Summary Aberrant glycosylation is a common feature of many cancers, and it plays
crucial roles in tumor development and biology. Cancer progression can be regulated by …

[图书][B] Applied animal endocrinology

EJ Squires - 2024 - cabidigitallibrary.org
This book explains the role of hormones in improving and monitoring the production,
performance, reproduction, behaviour and health of livestock animals, focusing on cattle …

Autoantibodies-enemies, and/or potential allies?

H Ma, C Murphy, CE Loscher… - Frontiers in Immunology, 2022 - frontiersin.org
Autoantibodies are well known as potentially highly harmful antibodies which attack the host
via binding to self-antigens, thus causing severe associated diseases and symptoms (eg …

IgG4 autoantibodies in organ-specific autoimmunopathies: reviewing class switching, antibody-producing cells, and specific immunotherapies

I Koneczny, J Tzartos, M Mané-Damas… - Frontiers in …, 2022 - frontiersin.org
Organ-specific autoimmunity is often characterized by autoantibodies targeting proteins
expressed in the affected tissue. A subgroup of autoimmunopathies has recently emerged …

Advances in phage display based nano immunosensors for cholera toxin

Y Li, K Yang, D Kong, J Ye - Frontiers in Immunology, 2023 - frontiersin.org
Cholera, a persistent global public health concern, continues to cause outbreaks in
approximately 30 countries and territories this year. The imperative to safeguard water …

Covalent penicillin-protein conjugates elicit anti-drug antibodies that are clonally and functionally restricted

LP Deimel, L Moynié, G Sun, V Lewis, A Turner… - nature …, 2024 - nature.com
Many archetypal and emerging classes of small-molecule therapeutics form covalent protein
adducts. In vivo, both the resulting conjugates and their off-target side-conjugates have the …

[HTML][HTML] Introduction on monoclonal antibodies

M Sadeghalvad, N Rezaei - Monoclonal Antibodies, 2021 - intechopen.com
Monoclonal antibodies (mAbs) are a group of antibodies produced by identical clones of B
lymphocytes against a particular antigen. mAbs are identical in several properties such as …

Expanding the Anti-Phl p 7 Antibody Toolkit: An Anti-Idiotype Nanobody Inhibitor

SK Vester, AM Davies, RL Beavil, BS Sandhar… - Antibodies, 2023 - mdpi.com
We have previously produced a toolkit of antibodies, comprising recombinant human
antibodies of all but one of the human isotypes, directed against the polcalcin family antigen …

Anti-idiotypic agonistic antibodies: candidates for the role of universal remedy

AK Stanova, VA Ryabkova, SV Tillib, VJ Utekhin… - Antibodies, 2020 - mdpi.com
Anti-idiotypic antibodies (anti-IDs) were discovered at the very beginning of the 20th century
and have attracted attention of researchers for many years. Nowadays, there are five known …