The extracellular matrix (ECM) is an integral component of all organs and plays a pivotal
role in tissue homeostasis and repair. While the ECM was long thought to mostly have …

Since the discovery of the nuclear factor kappa B (NF-ĸB) transcription factor 36 years ago,
many studies have linked the NF-ĸB signaling pathway to pathological and physiological …

The extracellular matrix (ECM) is a complex network of proteins and proteoglycans secreted
by keratinocytes, fibroblasts and immune cells. The function of the skin ECM has expanded …

Dysregulated macrophage responses and changes in tissue metabolism are hallmarks of
chronic inflammation in the skin. However, the metabolic cues that direct and support …

Extracellular ATP has been shown to play an important role in invasion and the epithelial‐
mesenchymal transition (EMT) process in breast cancer; however, the mechanism is …

Epidermolysis bullosa simplex (EBS) is a group of inherited keratinopathies that, in most
cases, arise due to mutations in keratins and lead to intraepidermal ruptures. The cellular …

Osteosarcoma is a common primary bone malignancy, and distant metastasis limited the
cure estimate during last decades. Detailed investigation of osteosarcoma metastasis is …

Skin consists of the epidermis and dermis, which are connected by a specialized basement
membrane—the epidermal basement membrane. Both the epidermal basement membrane …

The outcome of an inflammatory incident can hang in the balance between restoring health
and tissue integrity on the one hand, and promoting aberrant tissue homeostasis and …

Abstract Benzo [a] pyrene (B [a] P), a typical PAHs widely existing in the marine
environment, has been extensively studied for its immunotoxicity due to its persistence and …