HIV preexposure prophylaxis: a review

J Riddell, KR Amico, KH Mayer - Jama, 2018 - jamanetwork.com
Importance About 40 000 Americans and 2 million people worldwide are newly infected with
HIV each year. The combination antiretroviral regimen, tenofovir disoproxil fumarate …

Acute HIV-1 infection

MS Cohen, GM Shaw, AJ McMichael… - New England Journal …, 2011 - Mass Medical Soc
Acute HIV-1 Infection | New England Journal of Medicine Skip to main content Access provided
byTE WHATU ORA HEALTH NEW ZEALAND COUNTIES MANUKAU The New England …

On-demand preexposure prophylaxis in men at high risk for HIV-1 infection

JM Molina, C Capitant, B Spire, G Pialoux… - … England Journal of …, 2015 - Mass Medical Soc
Background Antiretroviral preexposure prophylaxis has been shown to reduce the risk of
human immunodeficiency virus type 1 (HIV-1) infection in some studies, but conflicting …

Efficacy, safety, and effect on sexual behaviour of on-demand pre-exposure prophylaxis for HIV in men who have sex with men: an observational cohort study

JM Molina, I Charreau, B Spire, L Cotte, J Chas… - The lancet HIV, 2017 - thelancet.com
Background Data for on-demand pre-exposure prophylaxis (PrEP) are scarce. We
implemented a cohort study to assess its efficacy, safety, and effect on sexual behaviour …

Antiretroviral prophylaxis for HIV prevention in heterosexual men and women

JM Baeten, D Donnell, P Ndase… - New England journal …, 2012 - Mass Medical Soc
Background Antiretroviral preexposure prophylaxis is a promising approach for preventing
human immunodeficiency virus type 1 (HIV-1) infection in heterosexual populations …

Preexposure chemoprophylaxis for HIV prevention in men who have sex with men

RM Grant, JR Lama, PL Anderson… - … England Journal of …, 2010 - Mass Medical Soc
Background Antiretroviral chemoprophylaxis before exposure is a promising approach for
the prevention of human immunodeficiency virus (HIV) acquisition. Methods We randomly …

Emtricitabine-tenofovir concentrations and pre-exposure prophylaxis efficacy in men who have sex with men

PL Anderson, DV Glidden, A Liu… - Science translational …, 2012 - science.org
Drug concentrations associated with protection from HIV-1 acquisition have not been
determined. We evaluated drug concentrations among men who have sex with men in a …

HIV pre-exposure prophylaxis (PrEP): a review of current knowledge of oral systemic HIV PrEP in humans

CD Spinner, C Boesecke, A Zink, H Jessen… - Infection, 2016 - Springer
Purpose Despite established HIV prevention strategies and broadly available diagnostic
strategies in developed western countries, rates of HIV new infections remain high …

Penetration of tenofovir and emtricitabine in mucosal tissues: implications for prevention of HIV-1 transmission

KB Patterson, HA Prince, E Kraft, AJ Jenkins… - Science translational …, 2011 - science.org
A mainstay of strategies to prevent HIV-1 transmission is to use antiretroviral therapy (ART)
for pre-exposure prophylaxis (PrEP). Critical to the design and interpretation of PrEP …

High acceptability of HIV pre-exposure prophylaxis but challenges in adherence and use: qualitative insights from a phase I trial of intermittent and daily PrEP in at-risk …

EM Van der Elst, J Mbogua, D Operario, G Mutua… - AIDS and Behavior, 2013 - Springer
This paper used qualitative methods to explore experiences of men who have sex with men
and female sex workers in Nairobi and Mtwapa, Kenya, who used oral pre-exposure …