Objective Summarize evidence for use of advanced MRI techniques as monitoring
biomarkers in the clinic, and highlight the latest bench-to-bedside developments. Methods …

This article aims to provide the reader with an overview of recent developments in Arterial
Spin Labeling (ASL) MRI techniques. A great deal of progress has been made in recent …

Objective Blood–brain barrier (BBB) breakdown has been suggested to be an early
biomarker in human cognitive impairment. However, the relationship between BBB …

Purpose Assessment of brain hemodynamics without exogenous contrast agents is of
increasing importance in clinical applications. This study aims to develop an MR perfusion …

Arterial spin labeling (ASL) is an MRI technique that was first proposed a quarter of a century
ago. It offers the prospect of non-invasive quantitative measurement of cerebral perfusion …

Arterial spin labeling (ASL) techniques are gaining popularity for visualizing and quantifying
cerebral blood flow (CBF) in a range of patient groups. However, most ASL methods lack …

Purpose In this study, the basic properties and requirements of time‐encoded
pseudocontinuous arterial spin labeling (te‐pCASL) are investigated. Also, the extra degree …

Purpose To assess the impact of the different post‐processing options in the calibration of
arterial spin labeling (ASL) data on perfusion quantification and its reproducibility. Theory …

Accurate assessment of cerebral perfusion is vital for understanding the hemodynamic
processes involved in various neurological disorders and guiding clinical decision‐making …

Abstract Arterial Spin Labeling (ASL) is a non-invasive, non-contrast, perfusion imaging
technique which is inherently SNR limited. It is, therefore, important to carefully design scan …