Diving head-first into brain intravital microscopy

AR Suthya, CHY Wong, JH Bourne - Frontiers in Immunology, 2024 - frontiersin.org
Tissue microenvironments during physiology and pathology are highly complex, meaning
dynamic cellular activities and their interactions cannot be accurately modelled ex vivo or in …

Endothelial cell CD36 mediates stroke-induced brain injury via BBB dysfunction and monocyte infiltration in normal and obese conditions

I Kim, H Ju, J Minkler, R Jiang, A Singh… - Journal of Cerebral …, 2023 - journals.sagepub.com
CD36 expressed in multiple cell types regulates inflammation, vascular function, and innate
immunity. Specifically, CD36 in microvascular endothelial cells (ECs) signals to elicit …

Immunologic Implications for Stroke Recovery: Unveiling the Role of the Immune System in Pathogenesis, Neurorepair, and Rehabilitation

G Hey, S Bhutani, MG Woolridge… - Journal of cellular …, 2023 - scientificarchives.com
Stroke is a debilitating neurologic condition characterized by an interruption or complete
blockage of blood flow to certain areas of the brain. While the primary injury occurs at the …

Neuroprotective Effects of the Lithium Salt of a Novel JNK Inhibitor in an Animal Model of Cerebral Ischemia–Reperfusion

IA Schepetkin, GA Chernysheva, OI Aliev, LN Kirpotina… - Biomedicines, 2022 - mdpi.com
The c-Jun N-terminal kinases (JNKs) regulate many physiological processes, including
inflammatory responses, morphogenesis, cell proliferation, differentiation, survival, and cell …

Inhibiting leukocyte‐endothelial cell interactions by Chinese medicine Tongxinluo capsule alleviates no‐reflow after arterial recanalization in ischemic stroke

S Liu, Z Zhang, Y He, L Kong, Q Jin… - CNS Neuroscience …, 2023 - Wiley Online Library
Aims Despite successful vascular recanalization in stroke, one‐fourth of patients have an
unfavorable outcome due to no‐reflow. The pathogenesis of no‐reflow is fully unclear, and …

Oxygen-loaded microbubble-mediated sonoperfusion and oxygenation for neuroprotection after ischemic stroke reperfusion

YJ Ho, HL Cheng, LD Liao, YC Lin, HC Tsai… - Biomaterials …, 2023 - spj.science.org
Background Ischemic stroke-reperfusion (S/R) injury is a crucial issue in the protection of
brain function after thrombolysis. The vasodilation induced by ultrasound (US)-stimulated …