SARS-CoV-2 NSP1 induces mRNA cleavages on the ribosome
Y Tardivat, P Sosnowski, A Tidu, E Westhof… - Nucleic Acids …, 2023 - academic.oup.com
In severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the non-structural
protein NSP1 inhibits translation of host mRNAs by binding to the mRNA entry channel of …
protein NSP1 inhibits translation of host mRNAs by binding to the mRNA entry channel of …
Antibody Binding Captures High Energy State of an Antigen: The Case of Nsp1 SARS-CoV-2 as Revealed by Hydrogen–Deuterium Exchange Mass Spectrometry
We describe an investigation using structural mass spectrometry (MS) of the impact of two
antibodies, 15497 and 15498, binding the highly flexible SARS-CoV-2 Nsp1 protein. We …
antibodies, 15497 and 15498, binding the highly flexible SARS-CoV-2 Nsp1 protein. We …