Clusterin (CLU) or APOJ is a multifunctional glycoprotein that has been implicated in several
physiological and pathological states, including Alzheimer's disease (AD). With a prominent …

Albumin has a long historical involvement in design of media for the successful culture of
mammalian cells, in both the research and commercial fields. The potential application of …

Clusterin, also known as apolipoprotein J, is a versatile chaperone molecule which contains
several amphipathic and coiled-coil α-helices, typical characteristics of small heat shock …

Genetic variation in clusterin gene, also known as apolipoprotein J, has been associated
with Alzheimer's disease (AD) through replicated genome-wide studies, and plasma …

Sustained activation of Akt kinase acts as a focal regulator to increase cell growth and
survival, which causes tumorigenesis including breast cancer. Statins, potent inhibitors of 3 …

Albuminuria is not only an important marker of chronic kidney disease but also a crucial
contributor to tubulointerstitial inflammation (TIF). In this study, we determined whether …

The biological functions of clusterin (CLU, also known as ApoJ, SGP2, TRPM-2, CLI) have
been puzzling the researchers since its first discovery in the early 80's. We know that CLU is …

Proteinuria is a prognostic indicator of progressive kidney disease and poor cardiovascular
outcomes. Abnormally filtered bioactive macromolecules interact with proximal tubular …

Clusterin (CLU) is an evolutionary conserved molecular chaperone present in different
human tissues and fluids and established to be a significant cancer regulator. It controls …

Resistance to anticancer agents is one of the primary impediments to effective cancer
therapy. Chemoresistance occurs not only to clinically established therapeutic agents but …