PLK4 homodimerization is required for CEP152 centrosome localization and spindle organization

H Kasera, P Singh - bioRxiv, 2023 - biorxiv.org
ABSTRACT Polo-Like Kinase 4 (PLK4) is a unique serine/threonine kinase family member
that homodimerizes using its cryptic polo-box (CPB) region. Homodimerization of PLK4 …

Yeast 2-hybrid assay for investigating the interaction between the centrosome proteins PLK4 and STIL

H Kasera, S Kumar, P Singh - Methods in Cell Biology, 2022 - Elsevier
Centrosomes act as a major microtubule-organizing center in many animal cells. This non-
membranous cell organelle is involved in a wide range of cell functions like division …

Identification and investigation of novel ALMS1 interaction partners in cilia-related processes

FJ Wörz - 2023 - tobias-lib.ub.uni-tuebingen.de
Cilia, small antennae, can be found on nearly every cell in the human body and are
important for human health and vision. Defects in cilia can lead to a variety of diseases, such …