Ever since its discovery by Windhaus, the importance of the active metabolite of vitamin D (1,
25-dihydroxyvitamin D 3; 1, 25-(OH) 2D 3) has been ever expanding. In this review, the …

Type 1 diabetes mellitus (T1DM) results from the destruction of pancreatic β-cells that is
mediated by the immune system. Multiple genetic and environmental factors found in …

The aim of this study is to determine the relationships of vitamin D with diabetes, insulin
resistance obesity, and metabolic syndrome. Intra cellular vitamin D receptors and the 1-α …

Vitamin D metabolizing enzymes and vitamin D receptors are present in many cell types
including various immune cells such as antigen-presenting-cells, T cells, B cells and …

Vitamin D deficiency has been linked to the onset of diabetes. This review summarizes the
role of Vitamin D in maintaining the normal release of insulin by the pancreatic beta cells (β …

Pancreatic β-cell dysfunction plays an important role in the pathogenesis of both type 1 and
type 2 diabetes. Insulin, which is produced in β-cells, is a critical regulator of metabolism …

Vitamin D plays a pivotal role in the regulation of calcium-phosphorus metabolism,
particularly during pediatric age when nutritional rickets and impaired bone mass acquisition …

Abstract Introduction: Adequate Vitamin D intake and its concentration in serum are
important for bone health and calcium–phosphate metabolism as well as for optimal function …

We aimed to increase our understanding of the genetic determinants of vitamin D levels by
undertaking a large-scale genome-wide association study (GWAS) of serum 25 …

It is now clear that vitamin D has important roles in addition to its classic effects on calcium
and bone homeostasis. As the vitamin D receptor is expressed on immune cells (B cells, T …