The elusive metric of lesion load

ML Seghier - Brain Structure and Function, 2023 - Springer
One of the widely used metrics in lesion-symptom mapping is lesion load that codes the
amount of damage to a given brain region of interest. Lesion load aims to reduce the …

[HTML][HTML] Reliability and validity of DTI-based indirect disconnection measures

AR Smits, MJE van Zandvoort, NF Ramsey… - NeuroImage: Clinical, 2023 - Elsevier
White matter connections enable the interaction within and between brain networks. Brain
lesions can cause structural disconnections that disrupt networks and thereby cognitive …

[HTML][HTML] Associations of lesion location, structural disconnection, and functional diaschisis with depressive symptoms post stroke

J Klingbeil, ML Brandt, A Stockert, P Baum… - Frontiers in …, 2023 - frontiersin.org
Introduction Post-stroke depressive symptoms (PSDS) are common and relevant for patient
outcome, but their complex pathophysiology is ill understood. It likely involves social …

Impaired discourse content in aphasia is associated with frontal white matter damage

J Ding, EL Middleton, D Mirman - Brain Communications, 2023 - academic.oup.com
Aphasia is a common consequence of stroke with severe impacts on employability, social
interactions and quality of life. Producing discourse-relevant information in a real-world …

Incremental Value of Stroke-Induced Structural Disconnection in Predicting Global Cognitive Impairment After Stroke

C Pan, G Chen, P Jing, G Li, Y Li, J Miao, W Sun… - Stroke, 2023 - Am Heart Assoc
Background: Poststroke cognitive impairment (PSCI) is highly prevalent in stroke survivors
and correlated with unfavorable clinical outcomes. This study aimed to identify the neural …

Predicting functional impairments with lesion‐derived disconnectome mapping: Validation in stroke patients with motor deficits

M Khalilian, M Roussel, O Godefroy… - European Journal of …, 2024 - Wiley Online Library
Focal structural damage to white matter tracts can result in functional deficits in stroke
patients. Traditional voxel‐based lesion‐symptom mapping is commonly used to localize …

[HTML][HTML] Data-driven biomarkers outperform theory-based biomarkers in predicting stroke motor outcomes

ER Olafson, C Sperber, KW Jamison, MD Bowren Jr… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Chronic motor impairments are a leading cause of disability after stroke. Previous studies
have predicted motor outcomes based on the degree of damage to predefined structures in …

[PDF][PDF] Perceptual Deviations as the Gate to the Workspace Environment and Completeness Extension

V Kolyada - 2024 - osf.io
There are many pathological and non-pathological conditions that can help to bring the
explanation of general characteristics and the dynamic of consciousness awareness and its …

[HTML][HTML] The effect of damage to the white matter network and premorbid intellectual ability on postoperative verbal short-term memory and functional outcome in …

K Ebina, M Matsui, M Kinoshita, D Saito, M Nakada - PLoS One, 2023 - journals.plos.org
Cognitive reserve is the capacity to cope with cognitive decline due to brain damage caused
by neurological diseases. Premorbid IQ has been investigated as a proxy for cognitive …

[PDF][PDF] BRAIN COMMUNICATIONS

J Lin, GC Smith, SV Gliske, M Zochowski, K Shedden… - 2024 - pdfs.semanticscholar.org
Every year, tens of millions of people around the world suffer from epilepsy. 1, 2 This
common neurological disorder affects people of all ages and is characterized by chronic …