Compounds incorporating the chromene scaffold are largely present in natural products and
display a wide variety of biological activities. Their low toxicity combined to the broad …

The coumarin (benzopyran-2-one, or chromen-2-one) ring system, present in many natural
products, displays diverse pharmacological properties. It has attracted the attention of …

The study of coumarin dates back to 1820 when coumarin was first extracted from tonka
bean by Vogel. Compounds containing coumarin backbone are a very important group of …

In this work, bioorthogonal and photodegradable hydrogels derived from norbornene (Nb)
functionalized hyaluronic acid and a water soluble coumarin-based cross-linker possessing …

Monoamine oxidase is a flavin enzyme that catalyzes the oxidation of monoamine
neurotransmitters in the brain. Various toxic by-products, aldehydes and hydrogen peroxide …

In the last few years, Monoamine oxidase (MAO) have emerged as a target for the treatment
of many neurodegenerative diseases including anxiety, depression, Alzheimer's, and …

This is an overview of the metabolic reactions of drugs, natural products, physiological
compounds, and other (general) chemicals catalyzed by flavin monooxygenase (FMO) …

Coumarins are the phytochemicals, which belong to the family of benzopyrone, that display
interesting pharmacological properties. Several natural, synthetic and semisynthetic …

A novel series of substituted chalcones were designed and synthesized to be evaluated as
selective human MAO-B inhibitors. A combination of either methylsulfonyl or trifluoromethyl …

Neuropsychiatric disorders, such as Alzheimer's disease (AD), Parkinson's disease (PD)
and depression, have seriously inconvenienced the lives of patients. Growing evidence …