CAR T-Cell-Based gene therapy for cancers: new perspectives, challenges, and clinical developments

MP Jogalekar, RL Rajendran, F Khan… - Frontiers in …, 2022 - frontiersin.org
Chimeric antigen receptor (CAR)-T cell therapy is a progressive new pillar in immune cell
therapy for cancer. It has yielded remarkable clinical responses in patients with B-cell …

Resistance to anti-angiogenic therapy in cancer—alterations to anti-VEGF pathway

Y Itatani, K Kawada, T Yamamoto, Y Sakai - International journal of …, 2018 - mdpi.com
Anti-angiogenic therapy is one of the promising strategies for many types of solid cancers.
Bevacizumab (Avastin), a recombinant humanized monoclonal antibody of vascular …

ICAM-1 and VCAM-1: Gatekeepers in various inflammatory and cardiovascular disorders

V Singh, R Kaur, P Kumari, C Pasricha, R Singh - Clinica Chimica Acta, 2023 - Elsevier
Leukocyte migration from the vascular compartment is critical for normal lymphocyte
recirculation in specific tissues and immune response in inflammatory locations. Leukocyte …

Endometrial receptivity markers, the journey to successful embryo implantation

H Achache, A Revel - Human reproduction update, 2006 - academic.oup.com
Human embryo implantation is a three-stage process (apposition, adhesion and invasion)
involving synchronized crosstalk between a receptive endometrium and a functional …

ICAM-1 signaling in endothelial cells

C Lawson, S Wolf - Pharmacological reports, 2009 - Elsevier
Abstract Intercellular adhesion molecule-1 (ICAM-1; CD54) is a 90 kDa member of the
immunoglobulin (Ig) superfamily and is critical for the firm arrest and transmigration of …

[HTML][HTML] Pathogenesis of atherosclerosis: A multifactorial process

RB Singh, SA Mengi, YJ Xu, AS Arneja… - Experimental & Clinical …, 2002 - ncbi.nlm.nih.gov
Atherosclerosis is a leading cause of mortality and morbidity in the western world. It has
been recognized for over a century, and the understanding of its pathogenesis has …

Regulation of intercellular adhesion molecule‐1 (CD54) gene expression

KA Roebuck, A Finnegan - Journal of leukocyte biology, 1999 - Wiley Online Library
Abstract Intercellular adhesion molecule‐1 (ICAM‐1, CD54) is an inducible cell adhesion
glycoprotein of the immunoglobulin supergene family expressed on the surface of a wide …

[HTML][HTML] Platelet lysate from whole blood-derived pooled platelet concentrates and apheresis-derived platelet concentrates for the isolation and expansion of human …

N Fekete, M Gadelorge, D Fürst, C Maurer… - …, 2012 - Taylor & Francis
Background aims. The clinical use of human mesenchymal stromal cells (MSC) requires ex
vivo expansion in media containing supplements such as fetal bovine serum or …

The human hair follicle immune system: cellular composition and immune privilege

T Christoph, S Müller‐Röver, H Audring… - British Journal of …, 2000 - academic.oup.com
The immunology of the hair follicle, its relationship with the 'skin immune system'and its role
in hair diseases remain biologically intriguing and clinically important. In this study, we …

Mitochondrial reactive oxygen species mediate lysophosphatidylcholine-induced endothelial cell activation

X Li, P Fang, Y Li, YM Kuo, AJ Andrews… - … , and vascular biology, 2016 - Am Heart Assoc
Objective—Hyperlipidemia-induced endothelial cell (EC) activation is considered as an
initial event responsible for monocyte recruitment in atherogenesis. However, it remains …