Anthracyclines have been important and effective treatments against a number of cancers
since their discovery. However, their use in therapy has been complicated by severe side …

Despite the exceptional progress in breast cancer pathogenesis, prognosis, diagnosis, and
treatment strategies, it remains a prominent cause of female mortality worldwide …

Simple Summary Despite recent therapeutic advances against cancer, many patients do not
respond well or respond poorly, to treatment and develop resistance to more than one anti …

The JAK/STAT3 signaling pathway plays an essential role in various types of cancers.
Activation of this pathway leads to increased tumorigenic and metastatic ability, the transition …

Following a diagnosis of breast cancer, the most immediate challenges in patient
management are the determination of prognosis and identification of the most appropriate …

Metastasis accounts for 90% of breast cancer mortality. Despite the significant progress
made over the past decade in cancer medicine our understanding of metastasis remains …

The first cancer-targeted microRNA (miRNA) drug—MRX34, a liposome-based miR-34
mimic—entered Phase I clinical trials in patients with advanced hepatocellular carcinoma in …

Inflammatory responses play pivotal roles in cancer development, including tumor initiation,
promotion, progression, and metastasis. Cytokines are now recognized as important …

Cancer is a daunting global problem confronting the world's population. The most frequent
therapeutic approaches include surgery, chemotherapy, radiotherapy, and more recently …

Lung cancer is a main cause of death all over the world with a high incidence rate.
Metastasis into neighboring and distant tissues as well as resistance of cancer cells to …