Endometriosis and cancer
H Kajiyama, S Suzuki, M Yoshihara, S Tamauchi… - Free Radical Biology …, 2019 - Elsevier
Endometriosis, characterized by the presence of extra-uterine endometrium, is a common
gynecologic disorder in reproductive-age women. Although the detailed molecular …
gynecologic disorder in reproductive-age women. Although the detailed molecular …
Genetic variants underlying risk of endometriosis: insights from meta-analysis of eight genome-wide association and replication datasets
BACKGROUND Endometriosis is a heritable common gynaecological condition influenced
by multiple genetic and environmental factors. Genome-wide association studies (GWASs) …
by multiple genetic and environmental factors. Genome-wide association studies (GWASs) …
Genome-wide association meta-analysis identifies new endometriosis risk loci
We conducted a genome-wide association meta-analysis of 4,604 endometriosis cases and
9,393 controls of Japanese and European ancestry. We show that rs12700667 on …
9,393 controls of Japanese and European ancestry. We show that rs12700667 on …
The association between endometriosis and ovarian cancer: a review of histological, genetic and molecular alterations
PS Munksgaard, J Blaakaer - Gynecologic oncology, 2012 - Elsevier
OBJECTIVE: This article represents a review of histologic and genetic findings in
endometriosis and describes the mechanisms whereby genetic and non-genetic factors …
endometriosis and describes the mechanisms whereby genetic and non-genetic factors …
Contents of endometriotic cysts, especially the high concentration of free iron, are a possible cause of carcinogenesis in the cysts through the iron-induced persistent …
K Yamaguchi, M Mandai, S Toyokuni, J Hamanishi… - Clinical Cancer …, 2008 - AACR
Purpose: Endometriotic cysts are known to transform into ovarian cancers, such as clear cell
and endometrioid carcinomas. We hypothesized that an iron-rich environment produced by …
and endometrioid carcinomas. We hypothesized that an iron-rich environment produced by …
A genome-wide association study identifies genetic variants in the CDKN2BAS locus associated with endometriosis in Japanese
S Uno, H Zembutsu, A Hirasawa, A Takahashi… - Nature …, 2010 - nature.com
Although the pathogenesis of endometriosis is not well understood, genetic factors have
been considered to have critical roles in its etiology. Through a genome-wide association …
been considered to have critical roles in its etiology. Through a genome-wide association …
Association between endometriosis and cancer: a comprehensive review and a critical analysis of clinical and epidemiological evidence
E Somigliana, F Parazzini, S Stoppelli… - Gynecologic …, 2006 - Elsevier
OBJECTIVE.: This review was aimed to critically evaluate observational, cohort, and case–
control studies performed so far in order to assess the association between endometriosis …
control studies performed so far in order to assess the association between endometriosis …
Aberrant methylation at HOXA10 may be responsible for its aberrant expression in the endometrium of patients with endometriosis
Y Wu, G Halverson, Z Basir, E Strawn, P Yan… - American journal of …, 2005 - Elsevier
OBJECTIVE: HOXA10, expressed in endometrium, plays an important role in uterine
receptivity at the time of implantation. In the endometrium of women with endometriosis, its …
receptivity at the time of implantation. In the endometrium of women with endometriosis, its …
[HTML][HTML] The relationship of endometriosis and ovarian malignancy: a review
OBJECTIVE: To review the malignant potential of endometriosis based on epidemiologic,
histopathologic, and molecular data. DESIGN: Literature review. RESULT (S): The …
histopathologic, and molecular data. DESIGN: Literature review. RESULT (S): The …
[HTML][HTML] Hereditary ovarian carcinoma: heterogeneity, molecular genetics, pathology, and management
HT Lynch, MJ Casey, CL Snyder, C Bewtra, JF Lynch… - Molecular …, 2009 - Elsevier
Hereditary ovarian cancer accounts for at least 5% of the estimated 22,000 new cases of this
disease during 2009. During this same time, over 15,000 will die from malignancy ascribed …
disease during 2009. During this same time, over 15,000 will die from malignancy ascribed …