Kinetic modeling and parametric imaging with dynamic PET for oncological applications: general considerations, current clinical applications, and future perspectives

A Dimitrakopoulou-Strauss, L Pan… - European journal of …, 2021 - Springer
Dynamic PET (dPET) studies have been used until now primarily within research purposes.
Although it is generally accepted that the information provided by dPET is superior to that of …

Long-axial field-of-view PET/CT: perspectives and review of a revolutionary development in nuclear medicine based on clinical experience in over 7000 patients

I Alberts, H Sari, C Mingels, A Afshar-Oromieh, T Pyka… - Cancer Imaging, 2023 - Springer
Recently introduced long-axial field-of-view (LAFOV) PET/CT systems represent one of the
most significant advancements in nuclear medicine since the advent of multi-modality …

Parametric image generation with the uEXPLORER total-body PET/CT system through deep learning

Z Huang, Y Wu, F Fu, N Meng, F Gu, Q Wu… - European Journal of …, 2022 - Springer
Purpose Total-body dynamic positron emission tomography/computed tomography
(PET/CT) provides much sensitivity for clinical imaging and research, bringing new …

Whole-body voxel-based internal dosimetry using deep learning

A Akhavanallaf, I Shiri, H Arabi, H Zaidi - European Journal of Nuclear …, 2021 - Springer
Purpose In the era of precision medicine, patient-specific dose calculation using Monte
Carlo (MC) simulations is deemed the gold standard technique for risk-benefit analysis of …

Normal values for 18F-FDG uptake in organs and tissues measured by dynamic whole body multiparametric FDG PET in 126 patients

AH Dias, AK Hansen, OL Munk, LC Gormsen - EJNMMI research, 2022 - Springer
Background Dynamic whole-body (D-WB) FDG PET/CT is a recently developed technique
that allows direct reconstruction of multiparametric images of metabolic rate of FDG uptake …

Clinical feasibility and impact of fully automated multiparametric PET imaging using direct Patlak reconstruction: evaluation of 103 dynamic whole-body 18F-FDG PET …

AH Dias, MF Pedersen, H Danielsen, OL Munk… - European Journal of …, 2021 - Springer
Purpose Functional imaging by standard whole-body (WB) 18 F-flurodeoxyglucose (FDG)
positron emission tomography (PET) is an integrated part of disease diagnostics. Recently, a …

Bone metastases are measurable: the role of whole-body MRI and positron emission tomography

DE Oprea-Lager, MCF Cysouw, R Boellaard… - Frontiers in …, 2021 - frontiersin.org
Metastatic tumor deposits in bone marrow elicit differential bone responses that vary with the
type of malignancy. This results in either sclerotic, lytic, or mixed bone lesions, which can …

Multiparametric dynamic whole-body PSMA PET/CT using [68Ga]Ga-PSMA-11 and [18F]PSMA-1007

AH Dias, MR Jochumsen, HD Zacho, OL Munk… - EJNMMI research, 2023 - Springer
Background Routine prostate-specific membrane antigen (PSMA) positron emission
tomography (PET) performed for primary staging or restaging of prostate cancer patients is …

Comparison between a dual-time-window protocol and other simplified protocols for dynamic total-body 18F-FDG PET imaging

Z Wang, Y Wu, X Li, Y Bai, H Chen, J Ding, C Shen… - EJNMMI physics, 2022 - Springer
Purpose Efforts have been made both to avoid invasive blood sampling and to shorten the
scan duration for dynamic positron emission tomography (PET) imaging. A total-body …

Unsupervised inter-frame motion correction for whole-body dynamic PET using convolutional long short-term memory in a convolutional neural network

X Guo, B Zhou, D Pigg, B Spottiswoode, ME Casey… - Medical image …, 2022 - Elsevier
Subject motion in whole-body dynamic PET introduces inter-frame mismatch and seriously
impacts parametric imaging. Traditional non-rigid registration methods are generally …