[HTML][HTML] Cystic fibrosis related diabetes: Pathophysiology, screening and diagnosis

A Granados, CL Chan, KL Ode, A Moheet… - Journal of Cystic …, 2019 - Elsevier
Cystic fibrosis related diabetes (CFRD) is a distinct form of diabetes that is associated with
significantly increased morbidity and mortality in the CF population. The primary etiology is …

Multifactorial basis and therapeutic strategies in metabolism-related diseases

JVS Guerra, MMG Dias, AJVC Brilhante, MF Terra… - Nutrients, 2021 - mdpi.com
Throughout the 20th and 21st centuries, the incidence of non-communicable diseases
(NCDs), also known as chronic diseases, has been increasing worldwide. Changes in …

[HTML][HTML] ISPAD Clinical Practice Consensus Guidelines 2022: management of cystic fibrosis‐related diabetes in children and adolescents

KL Ode, M Ballman, A Battezzati, A Brennan… - Pediatric …, 2022 - ncbi.nlm.nih.gov
Cystic Fibrosis (CF) was the most common fatal single-gene disorder in Caucasians.
However, CF is found in non-Caucasians, including people of 100% African descent, and …

Cystic Fibrosis–Related Diabetes Workshop: Research Priorities Spanning Disease Pathophysiology, Diagnosis, and Outcomes

MS Putman, AW Norris, RL Hull, MR Rickels… - Diabetes …, 2023 - Am Diabetes Assoc
Cystic fibrosis (CF) is a recessive disorder arising from mutations in the gene encoding the
cystic fibrosis transmembrane conductance regulator (CFTR) protein. CFTR is expressed in …

A tale of two pancreases: exocrine pathology and endocrine dysfunction

MR Rickels, AW Norris, RL Hull - Diabetologia, 2020 - Springer
The islets of Langerhans are well embedded within the exocrine pancreas (the latter
comprised of ducts and acini), but the nature of interactions between these pancreatic …

Animal and model systems for studying cystic fibrosis

BH Rosen, M Chanson, LR Gawenis, J Liu… - Journal of Cystic …, 2018 - Elsevier
The cystic fibrosis (CF) field is the beneficiary of five species of animal models that lack
functional cystic fibrosis transmembrane conductance regulator (CFTR) channel. These …

Cystic fibrosis-related diabetes and lung disease: an update

BJ Prentice, A Jaffe, S Hameed… - European …, 2021 - Eur Respiratory Soc
The development of cystic fibrosis-related diabetes (CFRD) often leads to poorer outcomes
in patients with cystic fibrosis including increases in pulmonary exacerbations, poorer lung …

Cystic fibrosis related diabetes (CFRD) in the era of modulators: A scoping review

B Prentice, M Nicholson, GY Lam - Paediatric Respiratory Reviews, 2023 - Elsevier
Cystic fibrosis-related diabetes (CFRD) is a common complication of CF that increases in
incidence as patients age. Poor glycemic control has been shown to negatively impact lung …

New concepts in the pathogenesis of cystic fibrosis–related diabetes

A Moheet, A Moran - The Journal of Clinical Endocrinology & …, 2022 - academic.oup.com
Context Cystic fibrosis–related diabetes (CFRD) is the most common extrapulmonary
complication of cystic fibrosis (CF). Approximately 40% of people with CF who are older than …

[HTML][HTML] Advances in cystic fibrosis-related diabetes: Current status and future directions

F Lurquin, M Buysschaert, V Preumont - Diabetes & Metabolic Syndrome …, 2023 - Elsevier
Aims The aim of this review is to give an update of the recent advances in the
pathophysiology, prognosis, diagnosis and treatments of cystic fibrosis-related diabetes …