Characterization of obesity-related diseases and inflammation using single cell immunophenotyping in two different diet-induced obesity models

Z Ruppert, P Neuperger, B Rákóczi, N Gémes… - International Journal of …, 2024 - nature.com
Background Obesity is a growing problem worldwide and a major risk factor for many
chronic diseases. The accumulation of adipose tissue leads to the release of significant …

Exerkines: opening the way to protecting ischemic heart

L Feng, B Li, Z Tian - Current Opinion in Physiology, 2023 - Elsevier
Exercise, effectively and safely, contributes to the rehabilitation of the ischemic heart. In the
field of cardiovascular health, it has attracted increasing attention because of lower cost and …

Exercise intensity and sex alter neurometabolic, transcriptional, and functional recovery following traumatic brain injury

BA White, JT Ivey, R Velazquez-Cruz, R Oliverio… - Experimental …, 2023 - Elsevier
Physical exercise represents a potentially inexpensive, accessible, and optimizable
rehabilitation approach to traumatic brain injury (TBI) recovery. However, little is known …

The kisspeptin-1 receptor antagonist peptide-234 aggravates uremic cardiomyopathy in a rat model

H Dinh, ZZA Kovács, F Márványkövi, M Kis… - Scientific Reports, 2023 - nature.com
Uremic cardiomyopathy is characterized by diastolic dysfunction, left ventricular hypertrophy
(LVH), and fibrosis. Dysregulation of the kisspeptin receptor (KISS1R)-mediated pathways …

[HTML][HTML] Exercise training after myocardial infarction increases survival but does not prevent adverse left ventricle remodeling and dysfunction in high-fat diet fed mice

CPV Da Silva, VK Shettigar, LA Baer, E Abay… - Life sciences, 2022 - Elsevier
Aims Aerobic exercise is an important component of rehabilitation after cardiovascular
injuries including myocardial infarction (MI). In human studies, the beneficial effects of …

[HTML][HTML] Endurance Exercise Prevented Diabetic Cardiomyopathy through the Inhibition of Fibrosis and Hypertrophy in Rats

S Shabab, M Mahmoudabady… - Reviews in …, 2024 - imrpress.com
Background: Exercise training could be essential in preventing pathological cardiac
remodeling in diabetes. Therefore, the effects of moderate-intensity continuous training …

[HTML][HTML] A High-Fat Diet Induces Epigenetic 1-Carbon Metabolism, Homocystinuria, and Renal-Dependent HFpEF

SC Tyagi - Nutrients, 2025 - mdpi.com
Background/Objectives: Chronic gut dysbiosis due to a high-fat diet (HFD) instigates cardiac
remodeling and heart failure with preserved ejection fraction (HFpEF), in particular …

Food readjustment plus exercise training improves cardiovascular autonomic control and baroreflex sensitivity in high‐fat diet‐fed ovariectomized mice

B Nascimento‐Carvalho, A Dos‐Santos… - Physiological …, 2023 - Wiley Online Library
Despite consensus on the benefits of food readjustment and/or moderate‐intensity
continuous exercise in the treatment of cardiometabolic risk factors, there is little evidence of …

Gender Differences of Visceral Fat Area to Hip Circumference Ratio for Insulin Resistance

H Cao, X Huang, B Luo, W Shi, H Li… - … Metabolic Syndrome and …, 2024 - Taylor & Francis
Introduction Not all type 2 diabetes mellitus (T2DM) patients exhibit insulin resistance (IR).
Our objective is to identify the most effective sex-specific index for predicting IR in T2DM …

Metformin Regulates Cardiac Ferroptosis to Reduce Metabolic Syndrome-Induced Cardiac Dysfunction

L Xu, W Li, Y Chen, S Liu, G Liu, W Luo, G Cao… - Applied Biochemistry …, 2024 - Springer
High-fat diet-induced metabolic syndrome (MetS) is closely associated with cardiac
dysfunction. Recent research studies have indicated a potential association between MetS …