Therapeutic implications of fibroblast growth factor receptor inhibitors in a combination regimen for solid tumors

H Luo, T Zhang, P Cheng, D Li… - Oncology …, 2020 - spandidos-publications.com
A number of novel drugs targeting the fibroblast growth factor receptor (FGFR) signaling
pathway have been developed, including mostly tyrosine kinase inhibitors, selective …

Integrative modelling of signalling network dynamics identifies cell type-selective therapeutic strategies for FGFR4-driven cancers

SY Shin, NJ Chew, M Ghomlaghi, AC Chüeh, Y Jeong… - bioRxiv, 2023 - biorxiv.org
Oncogenic FGFR4 signalling represents a potential therapeutic target in many cancer types,
including triple negative breast cancer (TNBC) and hepatocellular carcinoma (HCC) …

Integrative Modeling of Signaling Network Dynamics Identifies Cell Type–Selective Therapeutic Strategies for FGFR4-Driven Cancers

SY Shin, NJ Chew, M Ghomlaghi, AC Chüeh… - Cancer …, 2024 - aacrjournals.org
Oncogenic FGFR4 signaling represents a potential therapeutic target in various cancer
types, including triple-negative breast cancer and hepatocellular carcinoma. However …