The use of alternative strategies for enhanced nanoparticle delivery to solid tumors

M Izci, C Maksoudian, BB Manshian… - Chemical …, 2021 - ACS Publications
Nanomaterial (NM) delivery to solid tumors has been the focus of intense research for over a
decade. Classically, scientists have tried to improve NM delivery by employing passive or …

Magnetic nanoparticle-based drug delivery for cancer therapy

R Tietze, J Zaloga, H Unterweger, S Lyer… - Biochemical and …, 2015 - Elsevier
Nanoparticles have belonged to various fields of biomedical research for quite some time. A
promising site-directed application in the field of nanomedicine is drug targeting using …

Magnetic particle hyperthermia—a promising tumour therapy?

S Dutz, R Hergt - Nanotechnology, 2014 - iopscience.iop.org
We present a critical review of the state of the art of magnetic particle hyperthermia (MPH) as
a minimal invasive tumour therapy. Magnetic principles of heating mechanisms are …

Biodistribution and targeting properties of iron oxide nanoparticles for treatments of cancer and iron anemia disease

E Alphandéry - Nanotoxicology, 2019 - Taylor & Francis
IONP (iron oxide nanoparticles) commercialized for treatments of iron anemia or cancer
diseases can be administered at doses exceeding 1 g per patient, indicating their bio …

Immunological effects of iron oxide nanoparticles and iron-based complex drug formulations: Therapeutic benefits, toxicity, mechanistic insights, and translational …

A Shah, MA Dobrovolskaia - Nanomedicine: Nanotechnology, Biology and …, 2018 - Elsevier
Nanotechnology offers several advantages for drug delivery. However, there is the need for
addressing potential safety concerns regarding the adverse health effects of these unique …

Functionalized superparamagnetic iron oxide nanoparticles (SPIONs) as platform for the targeted multimodal tumor therapy

C Janko, T Ratschker, K Nguyen, L Zschiesche… - Frontiers in …, 2019 - frontiersin.org
Standard cancer treatments involve surgery, radiotherapy, chemotherapy, and
immunotherapy. In clinical practice, the respective drugs are applied orally or intravenously …

Development and characterization of magnetic iron oxide nanoparticles with a cisplatin-bearing polymer coating for targeted drug delivery

H Unterweger, R Tietze, C Janko, J Zaloga… - International journal …, 2014 - Taylor & Francis
A highly selective and efficient cancer therapy can be achieved using magnetically directed
superparamagnetic iron oxide nanoparticles (SPIONs) bearing a sufficient amount of the …

Selection of potential iron oxide nanoparticles for breast cancer treatment based on in vitro cytotoxicity and cellular uptake

JM Poller, J Zaloga, E Schreiber… - International journal …, 2017 - Taylor & Francis
Superparamagnetic iron oxide nanoparticles (SPIONs) are promising tools for the treatment
of different diseases. Their magnetic properties enable therapies involving magnetic drug …

Folic acid-decorated PEGylated magnetite nanoparticles as efficient drug carriers to tumor cells overexpressing folic acid receptor

C Movileanu, M Anghelache, M Turtoi, G Voicu… - International Journal of …, 2022 - Elsevier
The improved drug delivery systems (DDS) are needed for the targeted delivery of their
therapeutic cargo (biologically active protein/peptide molecules, nucleic acids, vaccines …

Nanomedicine applied to cardiovascular diseases: latest developments

VM Martín Giménez, DE Kassuha… - Therapeutic …, 2017 - journals.sagepub.com
Cardiovascular diseases are a major cause of disability and they are currently responsible
for a significant number of deaths in a large percentage of the world population. A large …