Multicomponent reactions (MCRs) are composed of three or more reagents in which the final
product has all or most of the carbon atoms from its starting materials. These reactions …

Multicomponent reactions 9i. e., those that engage three or more starting materials to form a
product that contains significant fragments of all of them), have been widely employed in the …

The use of metal–organic frameworks (MOFs) comprising custom-designed linkers/ligands
as efficient and recyclable heterogeneous catalysts is on the rise. However, the topologically …

An ecofriendly synthetic pathway for the synthesis of donepezil precursors is described.
Alternative energy sources were used for the total synthesis in order to improve yields …

The synthesis of amides is one of the most exploited reactions in pharmaceutical chemistry.
It usually requires stoichiometric activators, thus representing an impactful reaction …

Herein, a combination of heteropolyacids and ionic liquids as a catalytic system was studied
for the Biginelli multicomponent reaction; the positive ionic liquid effect associated with the …

A simple and novel methodology has been developed for the synthesis of 1, 3-bis
(carboxymethyl) imidazolium chloride [BCMIM][Cl] salt. The ionic salt [BCMIM][Cl] catalyzed …

Chiral cyclopentenones are important precursors in the asymmetric synthesis of target
molecules. In particular, C-2 amino cyclopentenones could be utilised as intermediates …

The development of novel synthetic routes to produce bioactive compounds starting from
renewable sources has become an important research area in organic and medicinal …

Bioactive dihydropyrimidinones (DHPs) were designed and synthesized by a
multicomponent Biginelli reaction. The reaction was catalyzed by the polarized surface of …