Hepatitis E virus: advances and challenges

I Nimgaonkar, Q Ding, RE Schwartz… - Nature Reviews …, 2018 - nature.com
At least 20 million hepatitis E virus (HEV) infections occur annually, with> 3 million
symptomatic cases and∼ 60,000 fatalities. Hepatitis E is generally self-limiting, with a case …

Molecular virology of hepatitis E virus

I Ahmad, RP Holla, S Jameel - Virus research, 2011 - Elsevier
This review details the molecular virology of the hepatitis E virus (HEV). While replicons and
in vitro infection systems have recently become available, a lot of information on HEV has …

Hepatitis E virus genome structure and replication strategy

SP Kenney, XJ Meng - Cold Spring …, 2019 - perspectivesinmedicine.cshlp.org
Hepatitis E virus (HEV) possesses many of the features of other positive-stranded RNA
viruses but also adds HEV-specific nuances, making its virus–host interactions unique. Slow …

Molecular biology and replication of hepatitis E virus

D Cao, XJ Meng - Emerging microbes & infections, 2012 - Taylor & Francis
Hepatitis E virus (HEV), a single-stranded, positive-sense RNA virus, is responsible for acute
hepatitis E epidemics in many developing countries, and the virus is also endemic in some …

[HTML][HTML] Structural and molecular biology of hepatitis E virus

B Wang, XJ Meng - Computational and Structural Biotechnology Journal, 2021 - Elsevier
Hepatitis E virus (HEV) is one of the most common causes of acute viral hepatitis, mainly
transmitted by fecal-oral route but has also been linked to fulminant hepatic failure, chronic …

Hepatitis E: an emerging disease

MT Pérez-Gracia, B Suay… - Infection, Genetics and …, 2014 - Elsevier
Currently, the infection with the hepatitis E virus represents the most frequent cause for acute
hepatitis and jaundice in the world. According to WHO estimations, around two billion …

Molecular biology and infection of hepatitis E virus

Y Nan, YJ Zhang - Frontiers in microbiology, 2016 - frontiersin.org
Hepatitis E virus (HEV) is a viral pathogen transmitted primarily via fecal-oral route. In
humans, HEV mainly causes acute hepatitis and is responsible for large outbreaks of …

hepatitis E—a concise review of virology, epidemiology, clinical presentation and therapy

MC Donnelly, L Scobie, CL Crossan… - Alimentary …, 2017 - Wiley Online Library
Summary Background Hepatitis E virus (HEV) is a leading cause of acute icteric hepatitis
and acute liver failure in the developing world. During the last decade, there has been …

Molecular virology of hepatitis E virus

RP Holla, I Ahmad, Z Ahmad… - Seminars in liver …, 2013 - thieme-connect.com
Hepatitis E virus (HEV) is the causative agent of hepatitis E. It is a nonenveloped virus with
a∼ 7.2 kilobases positive-stranded RNA genome. The molecular virology of HEV is getting …

[PDF][PDF] Suppression of interferon‐α signaling by hepatitis E virus

C Dong, M Zafrullah, T Mixson‐Hayden, X Dai… - …, 2012 - Wiley Online Library
The interferon (IFN) system is integral to the host response against viruses, and many
viruses have developed strategies to overcome its antiviral effects. The effects of hepatitis E …