Azobenzene photoswitches for biomolecules

AA Beharry, GA Woolley - Chemical Society Reviews, 2011 - pubs.rsc.org
The photoisomerization of azobenzene has been known for almost 75 years but only
recently has this process been widely applied to biological systems. The central challenge of …

Azobenzene-based small molecular photoswitches for protein modulation

M Zhu, H Zhou - Organic & biomolecular chemistry, 2018 - pubs.rsc.org
Molecular photoswitches are a class of chemical structures that can readily isomerize
between distinct geometries upon irradiation with light. Molecular photoswitches are utilized …

Photopharmacology: beyond proof of principle

WA Velema, W Szymanski… - Journal of the American …, 2014 - ACS Publications
Pharmacotherapy is often severely hindered by issues related to poor drug selectivity,
including side effects, environmental toxicity, and the emergence of resistance. Lack of …

Excited state non-adiabatic dynamics of large photoswitchable molecules using a chemically transferable machine learning potential

S Axelrod, E Shakhnovich… - Nature …, 2022 - nature.com
Light-induced chemical processes are ubiquitous in nature and have widespread
technological applications. For example, photoisomerization can allow a drug with a photo …

Optical control of PIEZO1 channels

FA Peralta, M Balcon, A Martz, D Biljali, F Cevoli… - Nature …, 2023 - nature.com
PIEZO proteins are unusually large, mechanically-activated trimeric ion channels. The
central pore features structural similarities with the pore of other trimeric ion channels …

Learning to fly: thermochemistry of energetic materials by modified thermogravimetric analysis and highly accurate quantum chemical calculations

NV Muravyev, KA Monogarov, IN Melnikov… - Physical Chemistry …, 2021 - pubs.rsc.org
The standard state enthalpy of formation and the enthalpy of sublimation are essential
thermochemical parameters determining the performance and application prospects of …

Phase transition enthalpy measurements of organic and organometallic compounds and ionic liquids. Sublimation, vaporization, and fusion enthalpies from 1880 to …

W Acree, JS Chickos - Journal of Physical and Chemical Reference …, 2017 - pubs.aip.org
This compendium completes a previous report published in 2016 [2016ACR/CHI] on phase
change enthalpies. Paper I of this compendium includes over 6600 organic compounds …

Photocontrolling peptide α helices

GA Woolley - Accounts of chemical research, 2005 - ACS Publications
Reversible optical control of protein structure and function offers the possibility of probing
and manipulating individual proteins within the complex environment of a living cell. As a …

Light-driven membrane assembly, shape-shifting, and tissue formation in chemically responsive synthetic cells

Y Lee, A Fracassi, NK Devaraj - Journal of the American Chemical …, 2023 - ACS Publications
Living systems create remarkable complexity from a limited repertoire of biological building
blocks by controlling assembly dynamics at the molecular, cellular, and multicellular level …

Critical re-evaluation of the O− H bond dissociation enthalpy in phenol

P Mulder, HG Korth, DA Pratt, GA DiLabio… - The Journal of …, 2005 - ACS Publications
The gas-phase O− H bond dissociation enthalpy, BDE, in phenol provides an essential
benchmark for calibrating the O− H BDEs of other phenols, data which aids our …