The endothelium, a cellular monolayer lining the blood vessel wall, plays a critical role in
maintaining multiorgan health and homeostasis. Endothelial functions in health include …

Patients with diabetes are at higher risk of cardiovascular diseases and cognitive
impairment. SGLT2 inhibitors (Empagliflozin, Canagliflozin, Dapagliflozin, Ertugliflozin …

Background. Sodium‐glucose cotransporter 2 (SGLT2) and dipeptidyl peptidase‐4 (DPP‐4)
inhibitors are glucose‐lowering drugs whose anti‐inflammatory properties have recently …

Sodium-glucose cotransporter 2 inhibitors (SGLT2i) are new oral drugs for the therapy of
patients with type 2 diabetes mellitus (T2DM). Research in the past decade has shown that …

Atherosclerosis is a progressive inflammatory disease leading to mortality and morbidity in
the civilized world. Atherosclerosis manifests as an accumulation of plaques in the intimal …

Given that the increase in the aging population has grown into one of the largest public
health issues, inflammation and oxidative stress, which are closely associated with the aging …

The antidiabetic drug canagliflozin is reported to possess several cardioprotective effects.
However, no studies have investigated protective effects of canagliflozin in isoprenaline …

Large placebo-controlled clinical trials have shown that sodium-glucose cotransporter-2
inhibitors (SGLT2i) delay the deterioration of renal function and reduce cardiovascular …

Background Recent studies have reported improved diastolic function in patients
administered sodium-glucose cotransporter 2 inhibitors (SGLT2i). We aimed to investigate …

Abstract Sodium glucose cotransporter 2 (SGLT-2) inhibitors are the latest class of
antidiabetic medications. They prevent glucose reabsorption in the proximal convoluted …