Tourette syndrome (TS) is a neuropsychiatric disorder involving motor and phonic tics.
Inhibitory control is a key issue in TS, and many disruptive or impulsive behaviors might …

Background Anatomically, cortical-basal ganglia-thalamo-cortical (CBGTC) circuits have an
essential role in the expression of tics. At the biochemical level, the proper conveyance of …

Dysfunction of the γ-aminobutyric acid-ergic system in Tourette syndrome may conceivably
underlie the symptoms of motor disinhibition presenting as tics and psychiatric …

Gilles de la Tourette syndrome is a neuropsychiatric disorder in which cortical disinhibition
has been proposed as a pathophysiological mechanism involved in the generation of tics …

Tourette syndrome (TS) is assumed to result from frontostriatal dysfunction, which would be
expected to result in impairments in neuropsychological functions. This possibility has been …

To the Editor: Deep brain stimulation (DBS) has been used in the treatment of severely
affected treatment-refractory patients with Tourette's syndrome. Visser-Vandewalle and …

After having examined the definition, clinical phenomenology, comorbidity,
psychopathology, and phenotypes in the first paper of this Series, here I discuss the …

Background Inhibitory deficits are often a matter of debate in the pathophysiology of Tourette
syndrome (TS). Previous neuropsychological studies on behavioral inhibition revealed …

Background: Evidence that tic behaviour in individuals with Tourette syndrome reflects
difficulties inhibiting prepotent motor actions is mixed. Response conflict tasks produce …

BACKGROUND: Tourette syndrome (TS) is characterized by dysfunctional connectivity
between prefrontal cortex and sub-cortical structures, and altered meso-cortical and/or meso …