Calcitonin gene-related peptide (CGRP) is a 37-amino acid neuropeptide. Discovered 30
years ago, it is produced as a consequence of alternative RNA processing of the calcitonin …

Our conceptual understanding of the molecular architecture of G-protein coupled receptors
(GPCRs) has transformed over the last decade. Once considered as largely independent …

G protein-coupled receptors (GPCRs) modulate diverse physiological and behavioral
signaling pathways by virtue of changes in receptor activation and inactivation states …

Adrenomedullin (AM) is a recently discovered regulatory peptide involved in many functions
including vasodilatation, electrolyte balance, neurotransmission, growth, and hormone …

Sensory neuropeptides have been proposed to play a key role in the pathogenesis of a
number of respiratory diseases such as asthma, chronic obstructive pulmonary disease or …

Calcitonin gene-related peptide (CGRP) is widely distributed in the central and peripheral
nervous system. Its highly diverse biological activities are mediated via the G protein …

Intermedin (IMD) is a novel peptide related to calcitonin gene‐related peptide (CGRP) and
adrenomedullin (AM). Proteolytic processing of a larger precursor yields a series of …

Adrenomedullin (ADM) is a 52‐amino acid multifunctional peptide, which belongs to the
calcitonin gene‐related peptide (CGRP) superfamily of vasoactive peptide hormones. ADM …

Calcitonin gene-related peptide and adrenomedullin belong to a structurally related
neuropeptide family and are potent vasodilators expressed in the trigeminovascular system …

The development, maintenance and metastasis of solid tumors are highly dependent on the
formation of blood and lymphatic vessels from pre-existing ones through a series of …