Neutrophils are the most abundant innate immune cell with critical anti-microbial functions.
Since the discovery of granulocytes at the end of the nineteenth century, the cells have been …

Intravenous IgG (IVIg) contains polyclonal immunoglobulin G (IgG) from thousands of
donors. It is administered at a low dose at regular intervals as antibody replacement therapy …

Asthma is characterized by airway inflammation rich in eosinophils. Airway eosinophilia is
associated with exacerbations and has been suggested to play a role in airway remodelling …

Fc γ receptors (FcγR) expressed on the surface of human leukocytes bind clusters of
immunoglobulin G (IgG) to induce a variety of responses. Many therapeutic antibodies and …

We present a novel single‐platform assay for determination of the absolute number of
human blood monocyte subpopulations, ie, the CD14++ CD16− and the CD14+ CD16++ …

Asthma is frequently characterized by eosinophil-rich airway inflammation. Airway
eosinophilia is associated with asthma exacerbations and likely plays a part in airway …

While the origin of the phrase “birds of a feather flock together” is unclear, it has been in use
for centuries and is typically employed to describe the phenomenon that people with similar …

Eosinophils have the capacity to regulate the function of T cell subsets. Our aim was to test
the hypothesis of the existence of a regulatory subset of eosinophils. Human eosinophils …

Our understanding of eosinophil biology, development, and regulation has dramatically
increased in the past decade, leading to new paradigms for the role of eosinophils in human …

The function of type 2 immunity and mechanisms underlying the initiation of type 2 immunity
after sepsis-induced lung injury remain unclear. Sphingosine-1-phosphate receptor 2 …