Rhesus macaques are an important animal model for the study of human disease and the
development of vaccines against HIV and AIDS. HIV vaccines have been benchmarked in …

The threat of unstoppable plagues, such as AIDS and Ebola, is always with us. In Europe,
the most devastating plagues were those from the Black Death pandemic in the 1300s to the …

Receptor binding largely governs HIV tropism since the presence of CD4 and an
appropriate coreceptor, most often CCR5 or CXCR4, is a prerequisite for efficient membrane …

Cellular attachment factors like the C-type lectins DC-SIGN and DC-SIGNR (collectively
referred to as DC-SIGN/R) can augment viral infection and might promote viral …

By using replication-defective vectors derived from human immunodeficiency virus type 1
(HIV-1), simian immunodeficiency virus (SIVmac), and murine leukemia virus (MuLV), all of …

Dendritic cells (DCs) efficiently bind and transmit human immunodeficiency virus (HIV) to
cocultured T cells and so may play an important role in HIV transmission. DC-SIGN, a novel …

Human and simian immunodeficiency viruses (HIV and SIV, respectively) use chemokine
receptors as coreceptors along with CD4 to mediate viral entry. Several orphan receptors …

HIV type 1 (HIV-1) uses the chemokine receptors CCR5 and CXCR4 as coreceptors for entry
into target cells. Here we show that the HIV-1 envelope gp120 (Env) activates multiple ionic …

A simian homologue of Kaposi's sarcoma–associated herpesvirus (KSHV), the eighth
human herpesvirus (HHV8), was isolated from a simian immunodeficiency virus (SIV) …

To investigate the basis for envelope (Env) determinants influencing simian
immunodeficiency virus (SIV) tropism, we studied a number of Envs that are closely related …