Progression and metastasis of lung cancer

HH Popper - Cancer and Metastasis Reviews, 2016 - Springer
Metastasis in lung cancer is a multifaceted process. In this review, we will dissect the
process in several isolated steps such as angiogenesis, hypoxia, circulation, and …

[HTML][HTML] A narrative review of tumor-associated macrophages in lung cancer: regulation of macrophage polarization and therapeutic implications

SS Sedighzadeh, AP Khoshbin, S Razi… - … lung cancer research, 2021 - ncbi.nlm.nih.gov
Lung cancer is the deadliest malignancy worldwide. An inflammatory microenvironment is a
key factor contributing to lung tumor progression. Tumor-Associated Macrophages (TAMs) …

Iron oxide nanoparticles inhibit tumour growth by inducing pro-inflammatory macrophage polarization in tumour tissues

S Zanganeh, G Hutter, R Spitler, O Lenkov… - Nature …, 2016 - nature.com
Until now, the Food and Drug Administration (FDA)-approved iron supplement ferumoxytol
and other iron oxide nanoparticles have been used for treating iron deficiency, as contrast …

Guidelines for regulated cell death assays: a systematic summary, a categorical comparison, a prospective

X Hu, Z Li, R Lin, J Shan, Q Yu, R Wang… - Frontiers in cell and …, 2021 - frontiersin.org
Over the past few years, the field of regulated cell death continues to expand and novel
mechanisms that orchestrate multiple regulated cell death pathways are being unveiled …

LncRNA‐MALAT1 promotes angiogenesis of thyroid cancer by modulating tumor‐associated macrophage FGF2 protein secretion

J Huang, L Ma, W Song, B Lu, Y Huang… - Journal of cellular …, 2017 - Wiley Online Library
Tumor‐associated macrophages (TAMs) in the tumor microenvironment have been
associated with enhanced tumor progression. In this study, we investigated the role and …

Long non-coding RNA NIFK-AS1 inhibits M2 polarization of macrophages in endometrial cancer through targeting miR-146a

Y Zhou, W Zhao, L Mao, Y Wang, L Xia, M Cao… - The international journal …, 2018 - Elsevier
Accumulating evidence suggested that tumor-associated macrophages played crucial roles
in the progression of endometrial cancer. The aim of this study was to determine the role of …

The microenvironment of lung cancer and therapeutic implications

V Mittal, T El Rayes, N Narula, TE McGraw… - Lung cancer and …, 2016 - Springer
The tumor microenvironment (TME) represents a milieu that enables tumor cells to acquire
the hallmarks of cancer. The TME is heterogeneous in composition and consists of cellular …

Nanoparticle interactions with the tumor microenvironment

Y Huai, MN Hossen, S Wilhelm… - Bioconjugate …, 2019 - ACS Publications
Compared to normal tissues, the tumor microenvironment (TME) has a number of aberrant
characteristics including hypoxia, acidosis, and vascular abnormalities. Many researchers …

Targeting FROUNT with disulfiram suppresses macrophage accumulation and its tumor-promoting properties

Y Terashima, E Toda, M Itakura, M Otsuji… - Nature …, 2020 - nature.com
Tumor-associated macrophages affect tumor progression and resistance to immune
checkpoint therapy. Here, we identify the chemokine signal regulator FROUNT as a target to …

Ratio of intratumoral macrophage phenotypes is a prognostic factor in epithelioid malignant pleural mesothelioma

R Cornelissen, LA Lievense, AP Maat, RW Hendriks… - PloS one, 2014 - journals.plos.org
Hypothesis The tumor micro-environment and especially the different macrophage
phenotypes appear to be of great influence on the behavior of multiple tumor types. M1 …