Mosquitoes use chemical cues to modulate important behaviors such as feeding, mating,
and egg laying. The primary chemosensory organs comprising the paired antennae …

The majority of the currently available insecticides target the nervous system and genetic
mutations of invertebrate neural proteins oftentimes yield deleterious consequences, yet the …

Stellera chamaejasme L. is a Chinese traditional herb. It has a long history and many
medicinal usages. Biflavones, one of the main active ingredients in S. chamaejasme's roots …

Background Voltage‐gated potassium channel Kv2 is the primarily delayed rectifier in insect
nerves and muscles involved in several crucial biological processes, including action …

Potential targets for new vector control insecticides are nerve and muscle potassium
channels. In this study, the activities of known potassium channel blockers (4-aminopyridine …

Potassium channels constitute a very diverse group involved in neural signaling, neuronal
activity, membrane potential maintenance, and action potential generation. Here, we tested …

New public health insecticides are urgently required to prevent the spread of vector-borne
disease. With the goal of identifying new K+-channel-directed mosquitocides, analogs of the …

A complete understanding of the physiological pathways critical for proper function of the
insect nervous system is still lacking. The recent development of potent and selective small …

Based on the success of diacyl-tert-butylhydrazines RH-5849 and RH-1266 in controlling
agricultural crop pests, we endeavored to synthesize our own diacylbenzyl-and …