Although malaria remains a big burden to many countries that it threatens their socio-
economic stability, particularly in the countries where malaria is endemic, there have been …

Malaria, one of the major infectious disease-causing sizeable morbidity, mortality and
economic loss worldwide. The main drawback for the failure to eradicate malaria is the …

Among the various known targets for the treatment of Leishmaniasis, dihydrofolate
reductase (DHFR) is an essential target which plays an important role in the folate metabolic …

Antimalarial drugs for the treatment of malaria are amongst the most counterfeit drugs in
third world countries. An analytical technique capable of rapid determination of active …

Carbocyclic carbenes (CCCs) are a class of nucleophilic carbenes which are very similar to
N‐heterocyclic carbenes (NHCs) in terms of their reactivity, but they do not contain a …

The substrate to the enzyme PfDHFR (Plasmodium falciparum Dihydrofolate Reductase) is a
small molecule dihydrofolate (DHF), it gets converted to tetrahydrofolate (THF) in the active …