Morpholine is a heterocycle featured in numerous approved and experimental drugs as well
as bioactive molecules. It is often employed in the field of medicinal chemistry for its …

This review focuses on recent advances in catalytic metal-free transfer hydrogenations. In
recent years dihydropyridines have been widely used as reducing agents in organocatalytic …

Morpholine is a frequently used heterocycle in medicinal chemistry and a privileged
structural component of bioactive molecules. This is mainly due to its contribution to a …

In this review, the pivotal achievements and recent advances in catalytic asymmetric aza‐
DAR reported up to 2020 are retrospectively considered and their potency for …

Superparamagnetic nanoparticles coated with silica gel or alternatively steel beads are new
fixed‐bed materials for flow reactors that efficiently heat reaction mixtures in an inductive …

Developing drugs for the central nervous system (CNS) requires fine chemical modifications,
as a strict balance between size and lipophilicity is necessary to improve the permeability …

A PdII‐catalyzed asymmetric aminohydroxylation of 1, 3‐dienes with N‐tosyl‐2‐
aminophenols was developed by making use of a chiral pyridinebis (oxazoline) ligand. The …

The review analyzes methods of synthesis of 1, 4-oxazines (morpholines) starting from
vicinal amino alcohols and their derivatives, oxiranes, and aziridines. Examples of using …

An asymmetric hydrogenation reaction of benzoxazinones has been accomplished via a
relay iron/chiral Brønsted acid catalysis. This approach provides a variety of chiral …