Sleep spindles: mechanisms and functions

LMJ Fernandez, A Lüthi - Physiological reviews, 2020 - journals.physiology.org
Sleep spindles are burstlike signals in the electroencephalogram (EEG) of the sleeping
mammalian brain and electrical surface correlates of neuronal oscillations in thalamus. As …

Neural circuitry of wakefulness and sleep

TE Scammell, E Arrigoni, JO Lipton - Neuron, 2017 - cell.com
Sleep remains one of the most mysterious yet ubiquitous animal behaviors. We review
current perspectives on the neural systems that regulate sleep/wake states in mammals and …

Oscillating circuitries in the sleeping brain

AR Adamantidis, C Gutierrez Herrera… - Nature Reviews …, 2019 - nature.com
Brain activity during sleep is characterized by circuit-specific oscillations, including slow
waves, spindles and theta waves, which are nested in thalamocortical or hippocampal …

Measures of resting state EEG rhythms for clinical trials in Alzheimer's disease: recommendations of an expert panel

C Babiloni, X Arakaki, H Azami, K Bennys… - Alzheimer's & …, 2021 - Wiley Online Library
Abstract The Electrophysiology Professional Interest Area (EPIA) and Global Brain
Consortium endorsed recommendations on candidate electroencephalography (EEG) …

The slow oscillation in cortical and thalamic networks: mechanisms and functions

GT Neske - Frontiers in neural circuits, 2016 - frontiersin.org
During even the most quiescent behavioral periods, the cortex and thalamus express rich
spontaneous activity in the form of slow (< 1 Hz), synchronous network state transitions …

Sleep-wake control and the thalamus

TC Gent, CLA Bassetti, AR Adamantidis - Current opinion in neurobiology, 2018 - Elsevier
Highlights•The midline and sensory thalami exhibit a dichotomy in sleep-wake control.•The
thalamus, including RTN acts as integrator of sub-cortical sleep wake inputs.•Frontally …

Thalamocortical synchronization during induction and emergence from propofol-induced unconsciousness

FJ Flores, KE Hartnack, AB Fath… - Proceedings of the …, 2017 - National Acad Sciences
General anesthesia (GA) is a reversible drug-induced state of altered arousal required for
more than 60,000 surgical procedures each day in the United States alone. Sedation and …

Neural oscillations demonstrate that general anesthesia and sedative states are neurophysiologically distinct from sleep

O Akeju, EN Brown - Current opinion in neurobiology, 2017 - Elsevier
Highlights•Neural oscillations provide a framework for comparing general anesthesia and
sleep.•Anesthetic drugs do not induce the physiological neural oscillations of sleep.•Non …

The human thalamus orchestrates neocortical oscillations during NREM sleep

T Schreiner, E Kaufmann, S Noachtar… - Nature …, 2022 - nature.com
A hallmark of non-rapid eye movement sleep is the coordinated interplay of slow oscillations
(SOs) and sleep spindles. Traditionally, a cortico-thalamo-cortical loop is suggested to …

UP-DOWN cortical dynamics reflect state transitions in a bistable network

D Jercog, A Roxin, P Bartho, A Luczak, A Compte… - Elife, 2017 - elifesciences.org
In the idling brain, neuronal circuits transition between periods of sustained firing (UP state)
and quiescence (DOWN state), a pattern the mechanisms of which remain unclear. Here we …