Analysis of anticancer drugs: a review

S Nussbaumer, P Bonnabry, JL Veuthey… - Talanta, 2011 - Elsevier
In the last decades, the number of patients receiving chemotherapy has considerably
increased. Given the toxicity of cytotoxic agents to humans (not only for patients but also for …

Biomarkers of occupational exposure do anticancer agents: a minireview

A Suspiro, J Prista - Toxicology letters, 2011 - Elsevier
The majority of anticancer agents has in common DNA-damaging properties and affects not
only target-cells but also non-tumour cells. Its genotoxicity has been demonstrated in …

Evaluation of antineoplastic drug exposure of health care workers at three university-based US cancer centers

TH Connor, DG DeBord, JR Pretty… - … of occupational and …, 2010 - journals.lww.com
Objective: This study evaluated health care worker exposure to antineoplastic drugs.
Methods: A cross-sectional study examined environmental samples from pharmacy and …

Antineoplastic drug contamination in the urine of Canadian healthcare workers

CY Hon, K Teschke, H Shen, PA Demers… - International Archives of …, 2015 - Springer
Purpose The purpose of this study was to quantify the urine concentration of non-
metabolized cyclophosphamide (CP), a commonly administered antineoplastic drug, among …

Antineoplastic drug contamination on the hands of employees working throughout the hospital medication system

CY Hon, K Teschke, PA Demers… - Annals of Occupational …, 2014 - academic.oup.com
We previously reported that antineoplastic drug contamination is found on various work
surfaces situated throughout the hospital medication system (process flow of drug within a …

Application and assessment of a regular environmental monitoring of the antineoplastic drug contamination level in pharmacies-the MEWIP project

TK Kiffmeyer, J Tuerk, M Hahn… - Annals of …, 2013 - academic.oup.com
A large-scale study was carried out in order to determine the contamination level of
antineoplastic drugs in pharmacies and to investigate the suitability and effects of wipe …

Reduction in surface contamination with cyclophosphamide in 30 US hospital pharmacies following implementation of a closed-system drug transfer device

PJM Sessink, J Trahan, JW Coyne - Hospital Pharmacy, 2013 - journals.sagepub.com
Purpose In a follow-up to a previous study, surface contamination with the antineoplastic
drug cyclophosphamide was compared in 30 US hospital pharmacies from 2004 to 2010 …

Evaluation of working practices and surface contamination with antineoplastic drugs in outpatient oncology health care settings

B Kopp, R Schierl, D Nowak - International archives of occupational and …, 2013 - Springer
Purpose Many antineoplastic drugs are classified as carcinogenic, mutagenic and
teratogenic for humans. Therefore, minimization of exposure is required to reduce health …

Occupational exposure to antineoplastic drugs in four Italian health care settings

C Sottani, B Porro, M Imbriani, C Minoia - Toxicology letters, 2012 - Elsevier
Exposure assessment of health care workers to antineoplastic drugs (ADs) is still an open
issue since new, critical, and emerging factors may put pharmacists who prepare hazardous …

An analysis to study trends in occupational exposure to antineoplastic drugs among health care workers

C Sottani, B Porro, M Comelli, M Imbriani… - … of Chromatography B, 2010 - Elsevier
The use of antineoplastic agents for the treatment of cancer and other non-neoplastic
diseases is an increasingly common practice in hospitals. As a result, workers involved with …