Background The mucins found as components of mucus gel layers at mucosal surfaces
throughout the body play roles in protection as part of the defensive barrier on an organ and …

The mucosal tissues of the gastrointestinal, respiratory, reproductive, and urinary tracts, and
the surface of the eye present an enormous surface area to the exterior environment. All of …

The airways mucus gel performs a critical function in defending the respiratory tract against
pathogenic and environmental challenges. In normal physiology, the secreted mucins, in …

Chronic obstructive pulmonary diseases (COPD), comprised of pulmonary emphysema,
chronic bronchitis, and structural and inflammatory changes of small airways, is a leading …

Mucins are large multifunctional glycoproteins whose primary functions are to protect and
lubricate the surfaces of epithelial tissues lining ducts and lumens within the human body …

Background Influenza virus binds to cell receptors via sialic acid (SA) linked glycoproteins.
They recognize SA on host cells through their haemagglutinins (H). The distribution of SA on …

Sialic acids (Sias) are regarded as receptors for influenza viruses and are usually bound to
galactose (Gal) in an α2–3 or α2–6 configuration. The detection of these Sia configurations …

Mucins represent a family of glycoproteins characterized by repeat domains and a dense O-
glycosylation. During the last two decades, the gene and peptide structures of various …

Oxidative stress and endoplasmic reticulum (ER) stress are related states that can occur in
cells as part of normal physiology but occur frequently in diseases involving inflammation. In …

Glycosylation is one of the most important modifications of proteins and lipids, and cell
surface glycoconjugates are thought to play important roles in a variety of biological …