Consciousness is essential to normal human life. In epileptic seizures consciousness is
often transiently lost, which makes it impossible for the individual to experience or respond …

Epilepsy is among the most common brain network disorders, and it is associated with
substantial morbidity and increased mortality. Although focal epilepsy was traditionally …

Intractable focal epilepsy is a devastating disorder with profound effects on cognition and
quality of life. Epilepsy surgery can lead to seizure freedom in patients with focal epilepsy; …

Functional magnetic resonance imaging (fMRI) has become the dominant means of
measuring behavior-related neural activity in the human brain. Yet the relation between the …

Generalized tonic–clonic seizures are among the most dramatic physiological events in the
nervous system. The brain regions involved during partial seizures with secondary …

Key points Sudden unexpected death in epilepsy is the leading cause of death in patients
with refractory epilepsy. Respiratory and cardiac impairment induced by a seizure have …

Over the last decade, several papers have focused on the construction of highly detailed
mouse high field magnetic resonance image (MRI) templates via non-linear registration to …

Various functional imaging tools have been used to detect epileptic activity in the neural
network underlying mesial temporal lobe epilepsy (mTLE). In the present fMRI study, a data …

Impaired consciousness requires altered cortical function. This can occur either directly from
disorders that impair widespread bilateral regions of the cortex or indirectly through effects …

Dynamic interactions between remote but functionally specialized brain regions enable
complex information processing. This intercortical communication is disrupted in the neural …