Nearly one-third of patients with epilepsy continue to have seizures despite optimal
medication management. Systems employed to detect seizures may have the potential to …

Epileptic seizures are manifestations of epilepsy, a serious brain dynamical disorder second
only to strokes. Of the world's/spl sim/50 million people with epilepsy, fully 1/3 have seizures …

The persistence of intractable neurological disorders necessitates novel therapeutic
solutions. We demonstrate the utility of direct in situ electrophoretic drug delivery to treat …

This paper describes an application of one-class support vector machine (SVM) novelty
detection for detecting seizures in humans. Our technique maps intracranial …

Epilepsy is a common chronic neurological disorder affecting∼ 1–2% of the population.
Despite the available treatment options (pharmacotherapy, surgery, and vagus nerve …

OBJECTIVE: A new method for automatic seizure detection and onset warning is proposed.
The system is based on determining the seizure probability of a section of EEG. Operation …

The unpredictability of seizures is a central problem for all patients suffering from
uncontrolled epilepsy. Recently, numerous methods have been suggested that claim to …

The need for novel, efficacious, antiseizure therapies is widely acknowledged. This study
investigates in humans the feasibility, safety, and efficacy of high‐frequency electrical …

There exist significant clinical and basic research needs for accurate, automated seizure
detection algorithms. These algorithms have translational potential in responsive …

Apparatuses and methods support multi-modal operation of a medical device system for a
nervous system disorder. The medical device system comprises an implanted component …