Coactivation of GR and NFKB alters the repertoire of their binding sites and target genes

NAS Rao, MT McCalman, P Moulos… - Genome …, 2011 - genome.cshlp.org
Glucocorticoid receptor (GR) exerts anti-inflammatory action in part by antagonizing
proinflammatory transcription factors such as the nuclear factor kappa-b (NFKB). Here, we …

Smyd3 is a transcriptional potentiator of multiple cancer-promoting genes and required for liver and colon cancer development

ME Sarris, P Moulos, A Haroniti, A Giakountis… - Cancer cell, 2016 - cell.com
Smyd3 is a protein methyltransferase implicated in cancer development. Here we show that
Smyd3 expression in mice is required for chemically induced liver and colon cancer …

Performance in omics analyses of blood samples in long-term storage: opportunities for the exploitation of existing biobanks in environmental health research

DGAJ Hebels, P Georgiadis, HC Keun… - Environmental …, 2013 - ehp.niehs.nih.gov
Background: The suitability for omic analysis of biosamples collected in previous decades
and currently stored in biobanks is unknown. Objectives: We evaluated the influence of …

Current knowledge on microarray technology-an overview

CN Naidu, Y Suneetha - Tropical Journal of Pharmaceutical Research, 2012 - ajol.info
The completion of whole genome sequencing projects has led to a rapid increase in the
availability of genetic information. In the field of transcriptomics, the emergence of microarray …

Emergent transcriptomic technologies and their role in the discovery of biomarkers of liver transplant tolerance

S Mastoridis, M Martínez-Llordella… - Frontiers in …, 2015 - frontiersin.org
Liver transplantation offers a unique window into transplant immunology due, in part, to the
considerable proportion of recipients who develop immunological tolerance to their allograft …

[图书][B] Sustainable Agriculture: Biotechniques in Plant Biology

JA Parray, MY Mir, N Shameem - 2019 - Springer
Dr. Javid Ahmad Parray is presently working as an assistant professor in the Department of
Environmental Science, Government SAM Degree College, Budgam District, Jammu and …

[HTML][HTML] The KLK5 protease suppresses breast cancer by repressing the mevalonate pathway

G Pampalakis, O Obasuyi, O Papadodima… - Oncotarget, 2014 - ncbi.nlm.nih.gov
Abstract Kallikrein-related peptidase 5 (KLK5) displays aberrant expression in cancer.
However, any functional association is missing. Here, we show that reconstitution of KLK5 …

The KUPKB: a novel Web application to access multiomics data on kidney disease

J Klein, S Jupp, P Moulos, M Fernandez… - The FASEB …, 2012 - Wiley Online Library
The information gathered from the large number of omics experiments in renal biology is
underexplored, as it is scattered over many publications or held in supplemental data. To …

Systems biology combining human-and animal-data miRNA and mRNA data identifies new targets in ureteropelvic junction obstruction

T Papadopoulos, A Casemayou, E Neau, B Breuil… - BMC Systems …, 2017 - Springer
Background Although renal fibrosis and inflammation have shown to be involved in the
pathophysiology of obstructive nephropathies, molecular mechanisms underlying evolution …

Comparative Meta‐Analysis of Transcriptomics Data during Cellular Senescence and In Vivo Tissue Ageing

K Voutetakis, A Chatziioannou… - Oxidative Medicine …, 2015 - Wiley Online Library
Several studies have employed DNA microarrays to identify gene expression signatures that
mark human ageing; yet the features underlying this complicated phenomenon remain …