Cisplatin and other platinum-based chemotherapeutic drugs have been used extensively for
the treatment of human cancers such as bladder, blood, breast, cervical, esophageal, head …

The current global health threat by the novel coronavirus disease 2019 (COVID-19) requires
an urgent deployment of advanced therapeutic options available. The role of …

Tumour heterogeneity remains a major challenge in cancer therapy owing to the different
susceptibility of cells to chemotherapy within a solid tumour. Cancer stem-like cells (CSCs) …

Cancer therapies often have narrow therapeutic indexes and involve potentially suboptimal
combinations due to the dissimilar physical properties of drug molecules. Nanomedicine …

Formulating drugs into nanoparticles offers many attractive advantages over free drugs
including improved bioavailability, minimized toxic side effects, enhanced drug delivery …

The platinum drugs, cisplatin, carboplatin, and oxaliplatin, prevail in the treatment of cancer,
but new platinum agents have been very slow to enter the clinic. Recently, however, there …

Coating the surface of nanoparticles with polyethylene glycol (PEG), or “PEGylation”, is a
commonly used approach for improving the efficiency of drug and gene delivery to target …

Abstract Development of drug‐delivery systems that selectively target neoplastic cells has
been a major goal of nanomedicine. One major strategy for achieving this milestone is to …

The application of nanoparticles (NPs) to drug delivery has led to the development of novel
nanotherapeutics for the treatment of various diseases including cancer. However, clinical …

Cancer nanotherapeutics are progressing at a steady rate; research and development in the
field has experienced an exponential growth since early 2000's. The path to the …