Alternative splicing of messenger RNA (mRNA) precursors contributes to genetic diversity by
generating structurally and functionally distinct transcripts. In a disease state, alternative …

A higher expression of MALAT1 has been reported in breast cancer. However, more studies
are needed to decipher the mechanisms by which this lncRNA imposes its oncogenic …

Cholangiocarcinoma (CCA) is an aggressive malignant tumor of the hepatobiliary system,
mainly originating from the cholangiocytes of small intrahepatic bile ducts [1]. The overall …

Breast cancer as the second most common cancer worldwide tend to be experienced by
Iranian women 10 years earlier with a peak incidence at the premenopausal stage. Genetic …

Metastasis is a well-known poor prognostic factor and primary cause of mortality in patients
with colorectal cancer (CRC). Recently, with the progress of high through-put sequencing …

Purpose A number of single nucleotide polymorphisms (SNPs) in EebB4 gene have been
studied, which has clarified their impact on breast cancer in different populations …

Objective Gastric cancer is a multifactorial disease. In addition to environmental factors,
many genes are involved in this malignancy. One of the genes associated with gastric …

Breast cancer is a major cause of cancer-related death in women worldwide. miRNAs are
new players of breast tumorigenesis, used as diagnostic and prognostic biomarkers. Among …

Background Overwhelming evidence has suggested that dysregulated long noncoding
RNAs (lncRNAs) play a critical modulating effect in the evolution of breast cancer (BRCA) …

A genetic variant may alter a gene expression level and as a result be associated with
pathological characteristics in breast cancer. In this research, the frequency and association …